5,6-dimethylchrysene
National Institutes of Health
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Both syn and anti dihydrodiol epoxides from 5-methylchrysene (5-MCDE) and 5,6-dimethylchrysene (5,6-DMCDE) were reacted under the…
We compared the tumor-initiating activities toward mouse skin of two structurally related polycyclic aromatic hydrocarbon diol…
The DNA adducts formed from the racemic syn and anti dihydrodiol epoxides of 5,6-dimethylchrysene were characterized through…
Dihydrodiol epoxides from 5,6-dimethylchrysene exhibit properties similar to those of fjord region-containing hydrocarbon…
Previous metabolism and DNA-binding studies indicated that 5,6-dimethylchrysene (5,6-diMeC) is metabolically activated in mouse…
In contrast to 5-methylchrysene and 5,9-dimethylchrysene, 5,6-dimethylchrysene and 5,7-dimethylchrysene are weak tumor initiators…
5,6-Dimethylchrysene (5,6-diMeC) is a weaker tumor initiator on mouse skin than 5-methylchrysene (5-MeC). To investigate the…
In previous studies, we have observed unexpected structure-tumorigenicity relationships among the dimethylchrysenes. Thus, 5,6…
The presence of a bay-region methyl group in carcinogenic polycyclic aromatic hydrocarbons leads to considerable distortion in…