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4-phosphoerythronate dehydrogenase activity

Known as: 4-phospho-D-erythronate:NAD+ 2-oxidoreductase activity, PdxB, 4-O-phosphoerythronate dehydrogenase activity 
Catalysis of the reaction: 4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H(+) + NADH. [EC:1.1.1.290, RHEA:18832]
National Institutes of Health

Papers overview

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2013
2013
Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum.
Malaria tropica is a devastating infectious disease caused by Plasmodium falciparum. This parasite synthesizes vitamin B6 de novo… 
2012
2012
Exploring inhibition of Pdx 1 , a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum
Shaun B. REEKSTING*†, Ingrid B. MÜLLER†, Pieter B. BURGER*, Emmanuel S. BURGOS‡, Laurent SALMON§, Abraham I. LOUW*, Lyn-Marie… 
2011
2011
A Simple Route for Synthesis of 4-Phospho-D-Erythronate.
2007
2007
Crystal structures of recombination-associated protein RdgC, 2-Nitropropane Dioxygenase, and D-Erythronate-4-Phosphate Dehydrogenase
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