4-phosphoerythronate dehydrogenase activity

Bacterial genomes encode hundreds to thousands of enzymes, most of which are specialized for particular functions. However, most… (More)

PdxB catalyzes the second step in the biosynthesis of pyridoxal phosphate by oxidizing 4-phospho-d-erythronate (4PE) to 2-oxo-3… (More)

This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial Share Alike 3.0… (More)

Pyridoxal-5'-phosphate (the active form of vitamin B6) is an essential cofactor in many enzymatic reactions. While animals lack… (More)

We propose a pathway leading from erythrose-4-phosphate and glutamate to nitrogen 1 and carbons 5,5', and 6 of the pyridoxine… (More)

We report the DNA sequence and in vivo transcription start of pdxB, which encodes a protein required for de novo biosynthesis of… (More)