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4-methoxyestradiol

Known as: Estra-1,3,5(10)-Triene-3,17-Diol, 4-Methoxy-, (17beta)-, 4-MeE2, 4-MeOE2 
An endogenous metabolite formed during the O-methylation of the highly carcinogenic catechol estrogen 4-hydroxyestradiol (4-OHE2) by catechol-O… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Estrogens and estrogen metabolites have important functions in cardiovascular and other physiology, yet the patterns of estrogen… Expand
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2011
2011
To study the roles of estrogens and estrogen metabolites (EMs) in breast carcinogenesis, we reported a quantitative liquid… Expand
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Highly Cited
2006
Highly Cited
2006
Packed column supercritical fluid chromatography with tandem mass spectrometry was used for the separation of estrone, estradiol… Expand
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2004
2004
We have developed a gas chromatography/mass spectrometry (GC/MS) assay to measure 17beta-estradiol (E) and its biologically… Expand
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Highly Cited
2003
Highly Cited
2003
Cytochrome P450 1A1 (CYP1A1) and 1B1 (CYP1B1) catalyze the oxidative metabolism of 17 beta-estradiol (E2) to catechol estrogens… Expand
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Highly Cited
2001
Highly Cited
2001
The oxidative metabolism of 17beta-estradiol (E2) and estrone (E1) to catechol estrogens (2-OHE2, 4-OHE2, 2-OHE1, and 4-OHE1) and… Expand
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2001
2001
The oxidative metabolism of 17 -estradiol (E2) and estrone (E1) to catechol estrogens (2-OHE2, 4-OHE2, 2-OHE1, and 4-OHE1) and… Expand
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2000
2000
In a previous study of nine human breast-derived cell lines, rates of metabolism of 17beta-estradiol (E(2)) were greatly enhanced… Expand
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Highly Cited
1998
Highly Cited
1998
Estradiol is an established antioxidant in vitro and in vivo. In contrast, prooxidant effects such as 8-hydroxylation of guanine… Expand
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Highly Cited
1994
Highly Cited
1994
Rates of microsomal 17 beta-estradiol (E2) hydroxylation at the C-2, -4, -6 alpha, and -15 alpha positions are each induced… Expand
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