4-methoxyestradiol

Known as: Estra-1,3,5(10)-Triene-3,17-Diol, 4-Methoxy-, (17beta)-, 4-MeE2, 4-MeOE2 
An endogenous metabolite formed during the O-methylation of the highly carcinogenic catechol estrogen 4-hydroxyestradiol (4-OHE2) by catechol-O… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2016
01219792016

Papers overview

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2013
2013
Estrogens and estrogen metabolites have important functions in cardiovascular and other physiology, yet the patterns of estrogen… (More)
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2007
2007
Epidemiological studies indicated that people exposed to dioxins were prone to the development of lung diseases including lung… (More)
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2007
2007
Estradiol (E(2)) accelerates oviductal egg transport through intraoviductal nongenomic pathways in cyclic rats and through… (More)
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2004
2004
Estrogens and their oxidative metabolites, the catechol estrogens, have been implicated in the development of breast cancer; yet… (More)
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2003
2003
Breast cancer patients frequently develop metastases. This process requires the degradation of extracellular matrix proteins… (More)
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Highly Cited
2001
Highly Cited
2001
The oxidative metabolism of 17beta-estradiol (E2) and estrone (E1) to catechol estrogens (2-OHE2, 4-OHE2, 2-OHE1, and 4-OHE1) and… (More)
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2000
2000
In a previous study of nine human breast-derived cell lines, rates of metabolism of 17beta-estradiol (E(2)) were greatly enhanced… (More)
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1998
1998
Estradiol is an established antioxidant in vitro and in vivo. In contrast, prooxidant effects such as 8-hydroxylation of guanine… (More)
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1994
1994
Rates of microsomal 17 beta-estradiol (E2) hydroxylation at the C-2, -4, -6 alpha, and -15 alpha positions are each induced… (More)
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1979
1979
The biological activity of a series of natural catechol estrogens was examined under conditions of continuous administration. 2… (More)
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