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4-hydroxyifosfamide

Known as: 4-hydroxy-ifosfamide 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Ifosfamide
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Influence of Short-Term Use of Dexamethasone on the Pharmacokinetics of Ifosfamide in Patients
Dexamethasone induces the hepatic cytochrome P450 3A and, therefore, is predicted to change the pharmacokinetics, activities, and… 
2004
2004
Hypersensitivity pneumonitis associated with the use of trofosfamide.
Trofosfamide (Ixoten; Baxter Oncology, Germany) is an alkylating agent that, as with other oxazaphosphorine derivatives, has to… 
2001
2001
Modulation of the cytochrome P450–mediated metabolism of ifosfamide by ketoconazole and rifampin
The autoinducible metabolic transformation of the anticancer agent ifosfamide involves activation through 4‐hydroxyifosfamide to… 
2001
2001
Distribution of ifosfamide and metabolites between plasma and erythrocytes.
The distribution of ifosfamide (IF) and its metabolites 2-dechloroethylifosfamide (2DCE), 3-dechloroethylifosfamide (3DCE), 4… 
1997
1997
Quantification of 4-hydroxyifosfamide in plasma of ifosfamide-treated mice
Purpose: Ifosfamide is becoming an important clinical anticancer drug. Meaningful pharmacology studies require quantification of… 
1995
1995
Oxime derivatives of the intermediary oncostatic metabolites of cyclophosphamide and ifosfamide: synthesis and deuterium labeling for applications to metabolite quantification.
There is ongoing interest in the selective, quantitative analysis of the cyclophosphamide metabolites 4-hydroxycyclophosphamide… 
1994
1994
Direct detection of the intracellular formation of carboxyphosphamides using nuclear magnetic resonance spectroscopy.
31P nuclear magnetic resonance (NMR) spectroscopy was used in conjunction with cell perfusion techniques to monitor the… 
1989
1989
Effects of N-substitution on the activation mechanisms of 4-hydroxycyclophosphamide analogues.
The activation mechanisms of the N-substituted 4-hydroxycyclophosphamide analogues 4-hydroxyifosfamide (2b), 4… 
1985
1985
Fluorometric determination of 4-hydroxyifosfamide in blood and urine.
A sensitive fluorometric method using 3-aminophenol was developed to measure 4-hydroxyifosfamide, the active metabolite of the… 
1983
1983
Further studies on the conversion of 4-hydroxyoxazaphosphorines to reactive mustards and acrolein in inorganic buffers.
The rates at which the 4-hydroxyoxazaphosphorines, 4-hydroxycyclophosphamide and 4-hydroxyifosfamide, are converted to reactive… 
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