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4-amidinophenylpyroracemic acid

Known as: 4-APPA, 4-amidinophenylpyruvic acid 
National Institutes of Health

Papers overview

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2002
2002
Recombinant human tryptases (rHTs) corresponding to R and ‚ isoforms were characterized. rHT‚ was similar to tryptase isolated… Expand
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Highly Cited
1999
Highly Cited
1999
Tryptases, the predominant serine proteinases of human mast cells, have recently been implicated as mediators in the pathogenesis… Expand
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1992
1992
Considerable circumstantial evidence has been provided by in vitro studies that tryptase (EC 3.4.21.59), a neutral serine… Expand
1985
1985
On application of carbon tetrachloride to rats disturbances of haemostasis were observed. Antithrombin III and 4… Expand
1983
1983
The antithrombotic effects of the synthetic thrombin inhibitor 4-amidinophenylpyruvic acid and the naturally occurring thrombin… Expand
1981
1981
There is reported on the possibilities of diaplacental influencing on the DIC arising from the hypoxia we provoked with the help… Expand
1976
1976
The influence of 4-amidinophenylpyruvic acid (APPA)--a synthetic thrombin inhibitor--on the incidence of disseminated… Expand
Highly Cited
1968
Highly Cited
1968
Derivatives of benzylamine and benzamidine were found to be competitive inhibitors of the proteolytic enzymes trypsin, plasmin… Expand