Skip to search formSkip to main contentSkip to account menu

4-amidinophenylpyroracemic acid

Known as: 4-APPA, 4-amidinophenylpyruvic acid 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Diverse stability and catalytic properties of human tryptase alpha and beta isoforms are mediated by residue differences at the S1 pocket.
Recombinant human tryptases (rHTs) corresponding to alpha and beta isoforms were characterized. rHTbeta was similar to tryptase… 
1986
1986
[Stabilization of donor blood with thrombin inhibitors].
The content of free calcium ions in stored blood can be maintained by stabilizing it with thrombin inhibitors. With regard to a… 
1985
1985
Changes of haemostaseological variables in carbon tetrachloride poisoning in rats.
On application of carbon tetrachloride to rats disturbances of haemostasis were observed. Antithrombin III and 4… 
1983
1983
Comparative study on the antithrombotic effects of a synthetic thrombin inhibitor and of heparin in animal models.
The antithrombotic effects of the synthetic thrombin inhibitor 4-amidinophenylpyruvic acid and the naturally occurring thrombin… 
1981
1981
[Diaplacental influence on the disseminated intravascular coagulation (DIC) in an asphyxia model. II. Influence on the vessel's content (author's transl)].
There is reported on the possibilities of diaplacental influencing on the DIC arising from the hypoxia we provoked with the help… 
1977
1977
[First clinical experiences with the small molecular synthetic thrombin inhibitor 4-amidinophenylpyruvic acid (APPA)].
1976
1976
[Effect of 4-amidinophenylpyruvic acid on the generalized Sanarelli-Shwartzman phenomenon].
The influence of 4-amidinophenylpyruvic acid (APPA)--a synthetic thrombin inhibitor--on the incidence of disseminated… 
1970
1970
[Antithrombin and antiplasmin effect of 4-amidinophenylpyruvic acid in vivo].
Highly Cited
1968
Highly Cited
1968
Comparative studies on the inhibition of trypsin, plasmin, and thrombin by derivatives of benzylamine and benzamidine.
Derivatives of benzylamine and benzamidine were found to be competitive inhibitors of the proteolytic enzymes trypsin, plasmin… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)