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4,5,6,7-tetrabromobenzimidazole

Known as: TBBZ cpd 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2012
01220032012

Related topics

Related topics

1 relation

Broader (1)

Benzimidazoles

Related mentions per year

Related mentions per year

1945-2018
19401960198020002020
4,5,6,7-tetrabromobenzimidazole
Benzimidazoles

Papers overview

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2013
2013
Inhibition of protein kinase CK2 reduces Cyp24a1 expression and enhances 1,25-dihydroxyvitamin D(3) antitumor activity in human prostate cancer cells.
Vitamin D has broad range of physiological functions and antitumor effects. 24-Hydroxylase, encoded by the CYP24A1 gene, is the… (More)
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2012
2012
Modified tetrahalogenated benzimidazoles with CK2 inhibitory activity are active against human prostate cancer cells LNCaP in vitro.
A series of novel CK2 inhibitors, tetrahalogenated benzimidazoles carrying an aminoalkylamino group at position 2, has been… (More)
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2010
2010
Synthesis and proapoptotic properties of new casein kinase II inhibitors.
Casein kinase II (CK2) is the most pleiotropic of all protein kinases with more than 300 substrates implicated in a wide variety… (More)
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2009
2009
Anti-Pentatrichomonas hominis activity of newly synthesized benzimidazole derivatives — in vitro studies
Pentatrichomonas hominis, a parasitic protozoan often detected in human diarrheic stools, is the cause of severe morbidity in… (More)
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2008
2008
New inhibitors of protein kinase CK2, analogues of benzimidazole and benzotriazole
Derivatives of 4,5,6,7-tetrabromobenzotriazole (TBBt) and 4,5,6,7-tetrabromobenzimidazole (TBBi) with IC50 in the low micromolar… (More)
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Review
2005
Review
2005
Tetrabromobenzotriazole (TBBt) and tetrabromobenzimidazole (TBBz) as selective inhibitors of protein kinase CK2: evaluation of their effects on cells and different molecular forms of human CK2.
The development of selective cell-permeable inhibitors of protein kinase CK2 has represented an important advance in the field… (More)
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2004
2004
Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole.
Casein kinase 2 (CK2) is a ubiquitous, essential, and highly pleiotropic protein kinase whose abnormally high constitutive… (More)
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2003
2003
Selectivity of 4,5,6,7-tetrabromobenzimidazole as an ATP-competitive potent inhibitor of protein kinase CK2 from various sources.
Like the previously reported 4,5,6,7-tetrabromobenzotriazole (TBBt), the structurally related 4,5,6,7-tetrabromobenzimidazole… (More)
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2003
2003
Polyhalogenobenzimidazoles: synthesis and their inhibitory activity against casein kinases.
A series of novel polyhalogenated benzimidazoles have been prepared by exhaustive bromination of a variety of 2-substituted… (More)
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