3-hydroxycoumarin
National Institutes of Health
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In the present work the origin of highly varied acidity of hydroxycoumarins (pKa values) has been for the first time investigated…
The structure-activity relationships of four hydroxycoumarins, two with the hydroxyl group on the aromatic ring of the molecule…
Since the development of matrix-assisted laser desorption/ionization (MALDI) mass spectrometry, this procedure has been…
Human cytochrome P450 (P450) enzymes metabolize a variety of endogenous and xenobiotic compounds, including steroids, drugs, and…
Coumarin, a widely used fragrance ingredient, is a rat liver and mouse lung toxicant. Species differences in toxicity are…
Coumarin is used widely as a fragrance constituent and is administered clinically in the treatment of certain lymphedemas and…
1. o-Hydroxyphenylacetaldehyde was the major metabolite of coumarin (1 mM) in rat, gerbil and human liver microsomes. 2…