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3-hydroxycoumarin

 
National Institutes of Health

Papers overview

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2017
2017
In the present work the origin of highly varied acidity of hydroxycoumarins (pKa values) has been for the first time investigated… Expand
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2015
2015
The structure-activity relationships of four hydroxycoumarins, two with the hydroxyl group on the aromatic ring of the molecule… Expand
Highly Cited
2010
Highly Cited
2010
Human cytochrome P450 (P450) enzymes metabolize a variety of endogenous and xenobiotic compounds, including steroids, drugs, and… Expand
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2005
2005
For more than 40 years coumarin has been successfully used in the therapy of chronic venous insufficiency (CVI). The occurrence… Expand
2004
2004
A series of hydroxylated 3-hydroxycoumarins was synthesised by the reaction of 3-aryl-2-hydroxypropenoic derivatives with boron… Expand
Highly Cited
2002
Highly Cited
2002
Coumarin, a widely used fragrance ingredient, is a rat liver and mouse lung toxicant. Species differences in toxicity are… Expand
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2000
2000
o-Hydroxyphenylacetaldehyde (o-HPA), the product of coumarin 3, 4-epoxide, was synthesized and its contribution to the… Expand
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1992
1992
  • J. Fentem, J. Fry
  • Xenobiotica; the fate of foreign compounds in…
  • 1992
  • Corpus ID: 8876549
1. o-Hydroxyphenylacetaldehyde was the major metabolite of coumarin (1 mM) in rat, gerbil and human liver microsomes. 2… Expand
1991
1991
1. The metabolism of [3-14C]coumarin has been studied in rat hepatic microsomes and with two purified cytochrome P-450 isoenzymes… Expand
Highly Cited
1969