3-hydroxyacyl-CoA dehydrogenase activity

Known as: beta-hydroxyacylcoenzyme A dehydrogenase activity, L-3-hydroxyacyl CoA dehydrogenase activity, beta-hydroxyacyl-coenzyme A synthetase activity 
Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H(+). [EC:1.1.1.35]
National Institutes of Health

Related topics

Related topics

2 relations
3-Hydroxyacyl CoA Dehydrogenases

Broader (1)

acetoacetyl-CoA reductase activity

Papers overview

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2017
2017
Methylene blue decreases mitochondrial lysine acetylation in the diabetic heart
Diabetic cardiomyopathy is preceded by mitochondrial alterations, and progresses to heart failure. We studied whether treatment… Expand
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1998
1998
Peroxisomal D-hydroxyacyl-CoA dehydrogenase deficiency: resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency.
Peroxisomes play an essential role in a number of different metabolic pathways, including the beta-oxidation of a distinct set of… Expand
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1998
1998
Control of mitochondrial beta-oxidation: sensitivity of the trifunctional protein to [NAD+]/[NADH] and [acetyl-CoA]/[CoA].
Isolated human mitochondrial trifunctional protein was incubated with 2-hexadecenoyl-CoA, CoA and NAD+ and the resultant CoA… Expand
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Highly Cited
1992
Highly Cited
1992
Human liver long-chain 3-hydroxyacyl-coenzyme A dehydrogenase is a multifunctional membrane-bound beta-oxidation enzyme of mitochondria.
We have purified to homogeneity the long-chain specific 3-hydroxyacyl-CoA dehydrogenase from mitochondrial membranes of human… Expand
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1991
1991
Evidence for a peroxisomal fatty acid beta-oxidation involving D-3-hydroxyacyl-CoAs. Characterization of two forms of hydro-lyase that convert D-(-)-3-hydroxyacyl-CoA into 2-trans-enoyl-CoA.
A novel D-(-)-3-hydroxyacyl-CoA hydro-lyase, forming 2-trans-enoyl-CoA and formerly designated as epimerase (EC 5.1.2.3), was… Expand
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1980
1980
Properties of mitochondria and peroxisomal enoyl-CoA hydratases from rat liver.
Mitochondrial and peroxisomal enoyl-CoA hydratases were purified from rat liver. The mitochondrial enzyme, with a molecular… Expand
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