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3,5-difluorotyrosine

Known as: Tyrosine, 3,5-difluoro, difluorotyrosine 
National Institutes of Health

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2 relations

Broader (1)

Tyrosine
analogs & derivatives

Papers overview

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2016
2016
Mechanistic investigations of the radical transport pathway in fluorotyrosine-substituted class Ia ribonucleotide reductases
Ribonucleotide reductase (RNR) catalyzes the reduction of nucleotides to 2'deoxynucleotides, providing the monomeric precursors… 
2015
2015
Fluorinated Aromatic Amino Acids Distinguish Cation-π Interactions from Membrane Insertion*
Background: Peripheral membrane proteins can interact with zwitterionic phospholipid headgroups or lipid tails. Results… 
2015
2015
Nano-size uni-lamellar lipodisq improved in situ auto-phosphorylation analysis of E. coli tyrosine kinase using 19F nuclear magnetic resonance
Among many of biophysical methods, F NMR spectroscopy has emerged as a powerful tool for characterizing protein structure… 
2013
2013
Modulation of Y [subscript 356] Photooxidation in E. Coli Class Ia Ribonucleotide Reductase by Y [subscript 731] Across the α [subscript 2] :β [subscript 2] Interface
Substrate turnover in class Ia ribonucleotide reductase (RNR) requires reversible radical transport across two subunits over 35 A… 
2008
2008
Synthesis of 3,5-difluorotyrosine-containing peptides: application in substrate profiling of protein tyrosine phosphatases.
Fully protected 3,5-difluorotyrosine (F2Y), Fmoc-F2Y(tBu)-OH, is efficiently prepared by a chemoenzymatic process and… 
2003
2003
The role of acidic dissociation of substrate's phenol group in the mechanism of tyrosine phenol-lyase.
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