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3',5'-cyclic diguanylic acid metabolic process

Known as: cyclic diguanylate metabolic process, 3',5'-cyclic diguanylic acid metabolism, cdiGMP metabolic process 
The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine. [CHEBI… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
c-di-GMP modulates type IV MSHA pilus retraction and surface attachment in Vibrio cholerae
Biofilm formation by Vibrio cholerae facilitates environmental persistence, and hyperinfectivity within the host. Biofilm… 
2016
2016
Regulation of biofilm formation and cellular buoyancy through modulating intracellular cyclic di‐GMP levels in engineered cyanobacteria
The second messenger cyclic dimeric (3′→5′) GMP (cyclic di‐GMP or c‐di‐GMP) has been implicated in the transition between motile… 
Review
2015
Review
2015
Establishing a Role for Bacterial Cellulose in Environmental Interactions: Lessons Learned from Diverse Biofilm-Producing Proteobacteria
Bacterial cellulose (BC) serves as a molecular glue to facilitate intra- and inter-domain interactions in nature. Biosynthesis of… 
Highly Cited
2015
Highly Cited
2015
Contribution of Physical Interactions to Signaling Specificity between a Diguanylate Cyclase and Its Effector
ABSTRACT Cyclic diguanylate (c-di-GMP) is a bacterial second messenger that controls multiple cellular processes. c-di-GMP… 
2015
2015
In Silico Discovery and In Vitro Validation of Catechol-Containing Sulfonohydrazide Compounds as Potent Inhibitors of the Diguanylate Cyclase PleD
ABSTRACT Biofilm formation is responsible for increased antibiotic tolerance in pathogenic bacteria. Cyclic di-GMP (c-di-GMP) is… 
Highly Cited
2014
Highly Cited
2014
The Diguanylate Cyclase SadC Is a Central Player in Gac/Rsm-Mediated Biofilm Formation in Pseudomonas aeruginosa
ABSTRACT Pseudomonas aeruginosa is a Gram-negative opportunistic human pathogen and a threat for immunocompromised and cystic… 
Highly Cited
2012
Highly Cited
2012
Minor Pilins of the Type IV Pilus System Participate in the Negative Regulation of Swarming Motility
ABSTRACT Pseudomonas aeruginosa exhibits distinct surface-associated behaviors, including biofilm formation, flagellum-mediated… 
2012
2012
A bacterial hemerythrin domain regulates the activity of a Vibrio cholerae diguanylate cyclase.
The first demonstrated example of a regulatory function for a bacterial hemerythrin (Bhr) domain is reported. Bhrs have a… 
Highly Cited
2011
Highly Cited
2011
Modulation of Pseudomonas aeruginosa surface-associated group behaviors by individual amino acids through c-di-GMP signaling.
Highly Cited
2005
Highly Cited
2005
Identification and Characterization of a Cyclic di-GMP-specific Phosphodiesterase and Its Allosteric Control by GTP*
Cyclic diguanylic acid (c-di-GMP) is a global second messenger controlling motility and adhesion in bacterial cells. Synthesis… 
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