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3',5'-cyclic diguanylic acid metabolic process

Known as: cyclic diguanylate metabolic process, 3',5'-cyclic diguanylic acid metabolism, cdiGMP metabolic process 
The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine. [CHEBI… Expand
National Institutes of Health

Papers overview

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2016
2016
Regulation of biofilm formation and cellular buoyancy through modulating intracellular cyclic di-GMP levels in engineered cyanobacteria.
The second messenger cyclic dimeric (3'→5') GMP (cyclic di-GMP or c-di-GMP) has been implicated in the transition between motile… Expand
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2016
2016
Complex Interplay between FleQ, Cyclic Diguanylate and Multiple σ Factors Coordinately Regulates Flagellar Motility and Biofilm Development in Pseudomonas putida
Most bacteria alternate between a free living planktonic lifestyle and the formation of structured surface-associated communities… Expand
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2015
2015
Contribution of Physical Interactions to Signaling Specificity between a Diguanylate Cyclase and Its Effector
ABSTRACT Cyclic diguanylate (c-di-GMP) is a bacterial second messenger that controls multiple cellular processes. c-di-GMP… Expand
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Highly Cited
2014
Highly Cited
2014
The Diguanylate Cyclase SadC Is a Central Player in Gac/Rsm-Mediated Biofilm Formation in Pseudomonas aeruginosa
Pseudomonas aeruginosa is a Gram-negative opportunistic human pathogen and a threat for immunocompromised and cystic fibrosis… Expand
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2014
2014
Deletion mutant library for investigation of functional outputs of cyclic diguanylate metabolism in Pseudomonas aeruginosa PA14.
We constructed a library of in-frame deletion mutants targeting each gene in Pseudomonas aeruginosa PA14 predicted to participate… Expand
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2014
2014
Engineering of Bacillus subtilis strains to allow rapid characterization of heterologous diguanylate cyclases and phosphodiesterases.
Microbial processes, including biofilm formation, motility, and virulence, are often regulated by changes in the available… Expand
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Highly Cited
2012
Highly Cited
2012
Minor pilins of the type IV pilus system participate in the negative regulation of swarming motility.
Pseudomonas aeruginosa exhibits distinct surface-associated behaviors, including biofilm formation, flagellum-mediated swarming… Expand
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2012
2012
A bacterial hemerythrin domain regulates the activity of a Vibrio cholerae diguanylate cyclase.
The first demonstrated example of a regulatory function for a bacterial hemerythrin (Bhr) domain is reported. Bhrs have a… Expand
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Highly Cited
2011
Highly Cited
2011
Modulation of Pseudomonas aeruginosa surface-associated group behaviors by individual amino acids through c-di-GMP signaling.
To colonize the cystic fibrosis lung, Pseudomonas aeruginosa establishes sessile communities referred to as biofilms. Although… Expand
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Highly Cited
2005
Highly Cited
2005
Identification and Characterization of a Cyclic di-GMP-specific Phosphodiesterase and Its Allosteric Control by GTP*
Cyclic diguanylic acid (c-di-GMP) is a global second messenger controlling motility and adhesion in bacterial cells. Synthesis… Expand
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