2q31-q33

OBJECTIVE Autism has a strong, complex genetic component, most likely involving several genes. Multiple genomic screens have… Expand

Type 1 diabetes is a common, multifactorial disease with strong familial clustering (genetic risk ratio [lambda(S)] approximately… Expand

Autism has a strong and complex genetic component, involving several genes. Genomic screens, including our own, have shown… Expand

BackgroundAnnotations of completely sequenced genomes reveal that nearly half of the genes identified are of unknown function… Expand

To identify novel retina-specific genes systematically, we are performing expression profiling of retina ESTs that have been… Expand

Familial primary pulmonary hypertension (PPH) is a rare autosomal dominant disease characterized by distinctive changes in… Expand

Primary pulmonary hypertension (PPH), an often fatal disorder, is characterized by sustained elevation of pulmonary artery… Expand

Graves' disease (GD) is an autoimmune thyroid disorder that is inherited as a complex trait. We have genotyped 77 affected sib… Expand

Autosomal recessive retinitis pigmentosa (ARRP) is a genetically heterogeneous disease. To date, mutations in four members of the… Expand

Previous genome-wide mapping studies have provided suggestive linkage evidence for several novel susceptibility loci responsible… Expand