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2B3-101
Known as:
Glutathione Pegylated Liposomal Doxorubicin Hydrochloride Formulation 2B3-101
A glutathione (GSH) pegylated, liposome-encapsulated preparation of the hydrochloride salt form of the anthracycline antineoplastic antibiotic…
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National Institutes of Health
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2015
2015
Abstract P6-16-04: Phase 1/2a study of glutathione PEGylated liposomal doxorubicin (2B3-101) in breast cancer patients with brain metastases
P. Aftimos
,
Bojana Milojkovic-Kerklaan
,
+13 authors
D. Brandsma
2015
Corpus ID: 58825838
Background: The incidence of brain metastases (BM) in breast cancer (BC) patients (pts) has increased over the past decade. The…
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2014
2014
NT-23PHASE 1/2A STUDY OF GLUTATHIONE PEGYLATED LIPOSOMAL DOXORUBICIN (2B3-101) IN BREAST CANCER PATIENTS WITH BRAIN METASTASES (BCBM) OR RECURRENT HIGH GRADE GLIOMAS (HGG)
B. M. Kerklaan
,
A. Jager
,
+13 authors
D. Brandsma
2014
Corpus ID: 76470088
BACKGROUND: Without active delivery across the blood-brain barrier, the efficacy of doxorubicin is limited in the treatment of…
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