2-methoxyestrone

Known as: 2-MeOE1, 3-Hydroxy-2-Methoxyestra-1,3,5(10)-Trien-17-One, 2-MeE1 
A metabolite formed during the methylation of 2-hydroxyestrone (2-OHE1) by catechol-O-methyltransferase (COMT), with potential anticarcinogenic and… (More)
National Institutes of Health

Papers overview

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2012
2012
Although estrogen and the enzymes responsible for its metabolism have been detected within the lung, the ability of this tissue… (More)
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2008
2008
Purpose:The aimof these studieswas to characterize the actionof STX140 in a P-glycoprotein ^ overexpressing tumor cell line both… (More)
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Highly Cited
2006
Highly Cited
2006
Purpose: We report the first phase I trials of 2-methoxyestradiol (2ME2, Panzem® Capsules, EntreMed, Rockville, MD), alone and in… (More)
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2006
2006
The bis-sulfamoylated derivative of 2-methoxyestradiol (2-MeOE2), 2-methoxyestradiol-3,17-O,O-bis-sulfamate (2-MeOE2bisMATE), has… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE To determine whether the preclinical antitumor and antiangiogenic activity of 2-methoxyestradiol can be translated to the… (More)
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Highly Cited
2001
Highly Cited
2001
The oxidative metabolism of 17beta-estradiol (E2) and estrone (E1) to catechol estrogens (2-OHE2, 4-OHE2, 2-OHE1, and 4-OHE1) and… (More)
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2000
2000
Most cancer cells are dependent on glucose uptake to fulfil their energy requirements. In the present investigation we have… (More)
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1982
1982
The nonuterotropic metabolite of estradiol, 2-hydroxyestrone, administered at noon of proestrus to four-day cycling rats… (More)
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1979
1979
The acid ionization constants of estrone (10.77), 17 beta-estradiol (10.71) and 2-methoxyestrone (10.81) have been determined… (More)
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1979
1979
An assay for the quantitative determination of 2-hydroxyestrone and 2-methoxyestrone in human urine is described. The analytical… (More)
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