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2-methoxyestrone

Known as: 2-MeOE1, 3-Hydroxy-2-Methoxyestra-1,3,5(10)-Trien-17-One, 2-MeE1 
A metabolite formed during the methylation of 2-hydroxyestrone (2-OHE1) by catechol-O-methyltransferase (COMT), with potential anticarcinogenic and… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Hydroxyestrones
NCIt Antineoplastic Agent Terminology

Papers overview

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2010
2010
Simultaneous determination of eight estrogens and their metabolites in serum using liquid chromatography with electrochemical detection.
Highly Cited
2008
Highly Cited
2008
STX140 Is Efficacious In vitro and In vivo in Taxane-Resistant Breast Carcinoma Cells
Purpose: The aim of these studies was to characterize the action of STX140 in a P-glycoprotein–overexpressing tumor cell line… 
Highly Cited
2002
Highly Cited
2002
2-methoxyestradiol induces interferon gene expression and apoptosis in osteosarcoma cells.
Highly Cited
2000
Highly Cited
2000
Differential effects of estrone and estrone-3-O-sulfamate derivatives on mitotic. Arrest, apoptosis, and microtubule assembly in human breast cancer cells.
There is considerable interest in the potential use of estrogen derivatives for the treatment and prevention of breast cancer. We… 
Highly Cited
1990
Highly Cited
1990
Stopped-flow investigation of antioxidant activity of estrogens in solution.
1989
1989
Cigarette smoking alters hepatic estrogen metabolism in men: implications for atherosclerosis.
1983
1983
Metabolism of 2-methoxyestrone in normal men.
We studied, in four normal men, the metabolism of 2-methoxyestrone (2-MeOE1) using pulse injections of either [3H]2MeOE1 (two men… 
1982
1982
Estrogens in seminal plasma of human and animal species: identification and quantitative estimation by gas chromatography-mass spectrometry associated with stable isotope dilution.
Highly Cited
1974
Highly Cited
1974
Mass fragmentographic determination of eleven estrogens in the body fluids of pregnant and nonpregnant subjects.
1963
1963
2-methoxyestrone as an estrogen metabolite in the human subject.
During the last 20–30 weeks of pregnancy, the level of 2-methoxyestrone in the urine of 4 subjects ranged from less than 25 μg/24… 
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