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2-chloromethyl-5-hydroxy-4-pyranone

Known as: 2-ClMe-5-HOP, 2-chloromethyl-5-hydroxy-4H-pyran-4-one, chlorokojic acid 
 
National Institutes of Health

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1 relation

Broader (1)

Pyrones

Papers overview

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2019
2019
Synthesis, computational molecular docking analysis and effectiveness on tyrosinase inhibition of kojic acid derivatives.
Tyrosinase inhibitors have become increasingly important as whitening agents and for the treatment of pigmentary disorders. In… Expand
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Highly Cited
2014
Highly Cited
2014
Synthesis, characterization, and antimicrobial activity of kojic acid grafted chitosan oligosaccharide.
A novel water-soluble chitosan oligosaccharide (COS) derivative, chitosan oligosaccharide/kojic acid grafts assigned as COS/KA… Expand
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2013
2013
Mannich bases of 7-piperazinylquinolones and kojic acid derivatives: synthesis, in vitro antibacterial activity and in silico study.
Novel Mannich bases of 7-piperazinylquinolones with kojic acid and chlorokojic acid were designed as new quinolone antibacterials… Expand
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2013
2013
Evaluation of bioactivities of chlorokojic acid derivatives against dermatophytes couplet with cytotoxicity.
In an attempt to find novel antifungal agents with improved activity, a series of compounds bearing 6-chloromethyl-3-hydroxy-2… Expand
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2013
2013
Design, synthesis and in vivo/in vitro screening of novel chlorokojic acid derivatives
A series of novel Mannich bases of chlorokojic acid (2-chloromethyl-5-hydroxy-4H-pyran-4-one) were synthesized and their… Expand
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2012
2012
Experimental and theoretical charge density study of the chemical bonding in chlorokojic acid crystal structure.
The experimental charge density in the chlorokojic acid crystal structure was investigated on the basis of high-resolution X-ray… Expand
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Highly Cited
2010
Highly Cited
2010
A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities.
A series of 6-chloromethyl-3-hydroxy-2-substituted 4H-pyran-4-one derivatives were synthesized and tested for their antimicrobial… Expand
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2010
2010
Synthesis and biological activities of new Mannich bases of chlorokojic acid derivatives
A novel series of 6-chloromethyl-3-hydroxy-2-substituted 4H-pyran-4-one derivatives were synthesized and tested for their… Expand
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1998
1998
Regulation of selected biological processes in neoplastic cell lines by halogen derivatives of 5-hydroxy-2-hydroxymethyl-4-pyranone.
The present study was undertaken to investigate the effects of eight halogen derivatives of 5-hydroxy-2-hydroxymethyl-4-pyranone… Expand
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1995
1995
Antileukemic activity of 4-pyranone derivatives.
In a search for new compounds possessing antitumor activity, we examined the effects of a group of oxygen containing heterocyclic… Expand
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