2,6-diisopropylphenyl-4-hydroxybutanote disodium phosphate
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Background Propofol is the most widely used intravenous sedative-hypnotic anesthetic in clinical practice. However, many serious… Expand OBJECTIVE
To estimate the median effective dose (EDs0) of oral administrated HX0969w, fospropofol disodium and propofol emulsion… Expand BACKGROUND:Phosphate ester prodrugs of propofol (fospropofol, HX0969W) were designed to avoid the unsatisfactory water solubility… Expand • Volume 118 • Number 4 www.anesthesia-analgesia.org 745 As a commonly used IV sedative hypnotic drug, propofol has rapid onset… Expand BACKGROUND
HX0969w is a novel water-soluble prodrug designed to release propofol and gamma-hydroxybutyrate (GHB) and has a… Expand The water-soluble derivatives of propofol have gained attention as a method to increase solubility of propofol. According to the… Expand OBJECTIVE To examine the effects of a new intravenous anesthetic HX0969w on spontaneous locomotor activity in mice.METHODS 60… Expand HX0969w is a novel carboxylate ester prodrug of propofol. After intravenous administration of HX0969w, the compound is rapidly… Expand