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2,6-diamino-8-purinol
Known as:
2,6-diamino-1,7-dihydro-8H-purin-8-one
, 2,6-diamino-8-oxopurine
National Institutes of Health
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Related topics
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2 relations
Broader (1)
2-Aminopurine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The discovery of 7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one (AZD7648), a potent and selective DNA-dependent protein kinase…
Frederick W. Goldberg
,
M. Finlay
,
+13 authors
E. Dean
Journal of Medicinal Chemistry
2019
Corpus ID: 209416544
DNA-PK is a key component within the DNA damage response, as it is responsible for recognizing and repairing double-strand DNA…
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2006
2006
7-But-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9-dihydro-purin-8-one Is a Novel Competitive and Selective Inhibitor of Dipeptidyl Peptidase IV with an Antihyperglycemic Activity
K. Yamazaki
,
N. Yasuda
,
+5 authors
Isao Tanaka
Journal of Pharmacology and Experimental…
2006
Corpus ID: 8788510
7-But-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9-dihydro-purin-8-one (ER-319711) is a novel dipeptidyl peptidase (DPP…
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1998
1998
Detection of 8-oxoguanine in cellular DNA using 2,6-diamino-8-oxopurine as an internal standard for high-performance liquid chromatography with electrochemical detection.
J. Ravanat
,
E. Gremaud
,
J. Markovic
,
R. Turesky
Analytical Biochemistry
1998
Corpus ID: 24229728
The quantitative aspect of the electrochemical detection method to detect 8-oxo-7,8-dihydroguanine (8-oxoGua) has been improved…
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Highly Cited
1995
Highly Cited
1995
Determination of 8-oxoguanine in DNA by gas chromatography--mass spectrometry and HPLC--electrochemical detection: overestimation of the background level of the oxidized base by the gas…
J. Ravanat
,
R. Turesky
,
E. Gremaud
,
L. Trudel
,
R. Stadler
Chemical Research in Toxicology
1995
Corpus ID: 31388583
Two analytical methods, one involving the combined use of reverse-phase HPLC and electrochemical detection (HPLC-EC) and one…
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1988
1988
Different methods of graphite electrode treatment and their effect on the electrochemical behavior of a small adsorbing biological molecule, 2,6-diamino-8-purinol.
L. Bodalbhai
,
A. Brajter-toth
Analytical Chemistry
1988
Corpus ID: 42658037
Effect of the method of electrode treatment and the electrode material on the behavior of the adsorbing small biological molecule…
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