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SummaryThe objective of this work was to study certain metabolic aspects of fluorine-substituted analogues of natural polyamines… Expand Treatment of laboratory animals bearing transplantable tumours with α‐difluoromethylornithine, an inhibitor of ornithine… Expand 1. 2-Fluoroputrescine has a high affinity for spermidine synthase (Km 12 microM) and obeys normal Michaelis-Menten kinetics. 2… Expand Investigations with the fluorinated spermidine analogues show clearly that these compounds have significant potential for… Expand 1. Injection of 2,2-difluoroputrescine (DFPut) into the yolk sac of chick embryos causes the formation of 6,6-difluorospermidine… Expand