Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

2'-deoxyzebularine

 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Cytidine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2′-Deoxyzebularine Analogues
APOBEC3 enzymes form part of the innate immune system by deaminating cytosine to uracil in single-stranded DNA (ssDNA) and… Expand
Is this relevant?
2019
2019
Selective inhibition of APOBEC3 enzymes by single-stranded DNAs containing 2'-deoxyzebularine.
To restrict pathogens, in a normal human cell, APOBEC3 enzymes mutate cytosine to uracil in foreign single-stranded DNAs. However… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2019
2019
Differential Inhibition of APOBEC3 DNA‐Mutator Isozymes by Fluoro‐ and Non‐Fluoro‐Substituted 2′‐Deoxyzebularine Embedded in Single‐Stranded DNA
Abstract The APOBEC3 (APOBEC3A‐H) enzyme family is part of the human innate immune system that restricts pathogens by scrambling… Expand
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
2014
2014
Efficient synthesis of 2'-deoxyzebularine and its α-anomer by the silyl method of N-glycosylation. Crystal structures and conformational study in solution.
2'-Deoxyzebularine and its α-anomer have been efficiently synthesized with relatively high stereoselectivity by a modified… Expand
Is this relevant?
2009
2009
Synthesis and hybridization properties of modified oligodeoxynucleotides carrying non-natural bases.
The impact of the presence of nonnatural bases on the properties of oligodeoxynucleotides has been studied. First… Expand
  • table 1
  • table 2
Is this relevant?
2008
2008
Activation of p16 gene silenced by DNA methylation in cancer cells by phosphoramidate derivatives of 2'-deoxyzebularine.
We report herein the application of the phosphoramidate ProTide technology to improve the metabolism of the DNA methytransferase… Expand
  • table 1
  • figure 1
  • table 2
  • figure 2
Is this relevant?
2004
2004
Synthesis, stability, and protonation studies of a self-complementary dodecamer containing the modified nucleoside 2'-deoxyzebularine.
The nucleoside 2'-deoxyzebularine (K) was incorporated into the self-complementary dodecamer 5'-CGTACGKGTACG-3' by solid-phase 2… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE