2'-deoxyzebularine
National Institutes of Health
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APOBEC3 enzymes form part of the innate immune system by deaminating cytosine to uracil in single-stranded DNA (ssDNA) and…
To restrict pathogens, in a normal human cell, APOBEC3 enzymes mutate cytosine to uracil in foreign single-stranded DNAs. However…
The APOBEC3 (APOBEC3A‐H) enzyme family is part of the human innate immune system that restricts pathogens by scrambling…
The impact of the presence of nonnatural bases on the properties of oligodeoxynucleotides has been studied. First…
We report herein the application of the phosphoramidate ProTide technology to improve the metabolism of the DNA methytransferase…
The nucleoside 2′‐deoxyzebularine (K) was incorporated into the self‐complementary dodecamer 5′‐CGTACGKGTACG‐3′ by solid‐phase 2…