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2'-deoxyaristeromycin

Known as: Cyclopentanemethanol, 4-(6-amino-9H-purin-9-yl)-2-hydroxy-, (1R-(1alpha,2beta,4alpha))- 
 
National Institutes of Health

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Broader (1)

Deoxyadenosines

Papers overview

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2002
2002
The Conformational Study of Two Carbocyclic Nucleosides: Why Carbocyclic Nucleic Acids (CarNAs) Form More Stable Duplexes with RNA than DNA Does
Abstract Replacement of the furanose moiety of DNA with a cyclopentene ring produces a modified sugar analogue: Carbocyclic… Expand
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2001
2001
The First Example of a Hoogsteen Basepaired DNA Duplex in Dynamic Equilibrium with a Watson-Crick Basepaired Duplex—A Structural (NMR), Kinetic and Thermodynamic Study
Abstract A single-point substitution of the O4′ oxygen by a CH2 group at the sugar residue of A 6 (i.e. 2′-deoxyaristeromycin… Expand
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2000
2000
Structure of an 11-mer DNA Duplex Containing the Carbocyclic Nucleotide Analog: 2′-Deoxyaristeromycin
Abstract 2′-deoxyaristeromycin (dAr) is a nucleoside analogue that is resistant to the action of DNA glycosylases. High… Expand
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1999
1999
A single carbocyclic nucleotide substitution in a 12mer DNA gives a Hoogsteen basepaired duplex (till 38 degrees C) and a hairpin (till 65 degrees C). A 600 MHz NMR spectroscopic study.
The impact of intramolecular stereoelectronic effects has been examined by comparison of the solution structures of natural oligo… Expand
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1998
1998
Synthesis of enzymatically noncleavable carbocyclic nucleosides for DNA-N-glycosylase studies.
Carbocyclic nucleosides have been of great interest as antiviral agents and in studies in the area of antisense technology. The… Expand
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1985
1985
Protected 2'-deoxyaristeromycin on polymer support: a substitute for the acid labile 2'-deoxyadenosine moiety at the 3'-terminus of oligodeoxynucleotides.
A modified nucleoside antibiotic on polymer support was employed in the solid-phase synthesis of two oligodeoxynucleotides to… Expand
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