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Abstract Replacement of the furanose moiety of DNA with a cyclopentene ring produces a modified sugar analogue: Carbocyclic… Expand Abstract A single-point substitution of the O4′ oxygen by a CH2 group at the sugar residue of A 6 (i.e. 2′-deoxyaristeromycin… Expand Abstract 2′-deoxyaristeromycin (dAr) is a nucleoside analogue that is resistant to the action of DNA glycosylases. High… Expand The impact of intramolecular stereoelectronic effects has been examined by comparison of the solution structures of natural oligo… Expand Carbocyclic nucleosides have been of great interest as antiviral agents and in studies in the area of antisense technology. The… Expand A modified nucleoside antibiotic on polymer support was employed in the solid-phase synthesis of two oligodeoxynucleotides to… Expand