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18F-FPPRGD2

Known as: 18F-FP-PEG3-RGD2, [18F] FPPRGD2, 18F-FP-PRGD2 
A radiopharmaceutical agent comprised of a pegylated dimeric arginine-glycine-aspartic acid (RGD)-based peptide labeled with 2-fluoropropionyl, with… 
National Institutes of Health

Papers overview

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2019
2019
18F-FPPRGD2 PET/CT in patients with metastatic renal cell cancer
PurposeThe usefulness of positron emission tomography/computed tomography (PET/CT) using (18F)-2-fluoropropionyl-labeled… 
2015
2015
Pilot prospective evaluation of 18F-FPPRGD2 PET/CT in patients with cervical and ovarian cancer
PurposeWe report the effect of antiangiogenic therapy on the biodistribution of 18F-FPPRGD2 (a surrogate biomarker of integrin αv… 
2015
2015
Biodistribution of the 18F-FPPRGD2 PET radiopharmaceutical in cancer patients: an atlas of SUV measurements
PurposeThe aim of this study was to investigate the biodistribution of 2-fluoropropionyl-labeled PEGylated dimeric arginine… 
Review
2014
Review
2014
(18)F-FPPRGD2 PET/CT: pilot phase evaluation of breast cancer patients.
PURPOSE To present data from the first prospective pilot phase trial of breast cancer participants imaged with fluorine 18 ((18)F… 
2014
2014
Stability Analysis of Glutamic Acid Linked Peptides Coupled to NOTA through Different Chemical Linkages
Glutamic acid is a commonly used linker to form dimeric peptides with enhanced binding affinity than their corresponding… 
2012
2012
Quantitative Analysis and Parametric Imaging of 18F-Labeled Monomeric and Dimeric RGD Peptides Using Compartment Model
PurposeNon-invasive PET imaging with radiolabeled RGD peptides for αvβ3 integrin targeting has become an important tool for tumor… 
Highly Cited
2011
Highly Cited
2011
18F-FPPRGD2 and 18F-FDG PET of Response to Abraxane Therapy
Abraxane (nanoparticle albumin-bound paclitaxel) is an anticancer drug approved by the Food and Drug Administration. However, the… 
2011
2011
N-Succinimidyl 4-[18F]-fluoromethylbenzoate-labeled dimeric RGD peptide for imaging tumor integrin expression
RGD peptides, radiolabeled with 18F, have been used in the clinic for PET imaging of tumor angiogenesis in cancer patients. RGD… 
2011
2011
PET imaging of early response to the tyrosine kinase inhibitor ZD4190
PurposeWe evaluated noninvasive positron emission tomography (PET) imaging for monitoring tumor response to the VEGFR-2 tyrosine… 
Highly Cited
2009
Highly Cited
2009
18F-Labeled Galacto and PEGylated RGD Dimers for PET Imaging of αvβ3 Integrin Expression
PurposeIn vivo imaging of αvβ3 has important diagnostic and therapeutic applications. 18F-Galacto-arginine–glycine–aspartic acid… 
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