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18-oxocortisol

Known as: 11 beta,17 alpha,21-trihydroxy-3,20-diketo-4-pregnene-18-al, Pregn-4-en-18-al, 11,17,21-trihydroxy-3,20-dioxo-, (11beta)- 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Adrenal venous sampling is currently the only reliable method to distinguish unilateral from bilateral diseases in primary… Expand
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Highly Cited
2012
Highly Cited
2012
CONTEXT Diagnosis of primary aldosteronism (PA) is made by screening, confirmation testing, and subtype diagnosis (computed… Expand
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Highly Cited
2011
Highly Cited
2011
CONTEXT 18-Oxocortisol (18-oxoF) is a derivative of cortisol (F) that is produced by aldosterone synthase (CYP11B2). The… Expand
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2004
2004
18-Hydroxycortisol (18-OHF) and 18-oxocortisol (18-oxoF) are derivatives of cortisol found in primary aldosteronism but whose… Expand
Highly Cited
1998
Highly Cited
1998
CYP11B1 (11beta-hydroxylase) and CYP11B2 (aldosterone synthase) are 93% identical mitochondrial enzymes that both catalyze 11beta… Expand
Highly Cited
1992
Highly Cited
1992
A gene encoding steroid 18-hydroxylase (P-450C18) was isolated from a human genomic DNA library. It was identified as CYP11B2… Expand
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1986
1986
The hypertensogenic effect of 18-oxocortisol, an aldosterone analogue possessing both mineralocorticoid and glucocorticoid… Expand
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Highly Cited
1984
Highly Cited
1984
A radioimmunoassay procedure for the measurement of urinary 18-oxocortisol was developed. The antibody was raised against 18… Expand
Highly Cited
1983
Highly Cited
1983
Aldosterone-biosynthesizing adrenal tissue contains an angular methyl oxidase which converts corticosterone to 18… Expand
1983
1983
Two C-18-oxygenated corticosteroids, 18-hydroxy- and 18-oxocortisol, have recently been isolated from the urine of patients with… Expand