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18-oxocortisol

Known as: 11 beta,17 alpha,21-trihydroxy-3,20-diketo-4-pregnene-18-al, Pregn-4-en-18-al, 11,17,21-trihydroxy-3,20-dioxo-, (11beta)- 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Hydrocortisone
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Studies on the origin of circulating 18-hydroxycortisol and 18-oxocortisol in normal human subjects.
18-Hydroxycortisol (18-OHF) and 18-oxocortisol (18-oxoF) are derivatives of cortisol found in primary aldosteronism but whose… 
Highly Cited
1998
Highly Cited
1998
Recombinant CYP11B genes encode enzymes that can catalyze conversion of 11-deoxycortisol to cortisol, 18-hydroxycortisol, and 18-oxocortisol.
CYP11B1 (11beta-hydroxylase) and CYP11B2 (aldosterone synthase) are 93% identical mitochondrial enzymes that both catalyze 11beta… 
Highly Cited
1993
Highly Cited
1993
The unique steroidogenesis of the aldosteronoma in the differential diagnosis of primary aldosteronism.
18-Hydroxycortisol and 18-oxocortisol have been isolated from the urine of patients with aldosterone producing adrenocortical… 
Highly Cited
1992
Highly Cited
1992
Role of steroid 11 beta-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humans.
A gene encoding steroid 18-hydroxylase (P-450C18) was isolated from a human genomic DNA library. It was identified as CYP11B2… 
1991
1991
Measurement of 4 urinary C-18 oxygenated corticosteroids by stable isotope dilution mass fragmentography
1987
1987
Role of 18-hydroxylated cortisols in hypertension.
1986
1986
Hypertensive potency of 18-oxocortisol in the rat.
The hypertensogenic effect of 18-oxocortisol, an aldosterone analogue possessing both mineralocorticoid and glucocorticoid… 
Highly Cited
1984
Highly Cited
1984
Elevated urinary excretion of 18-oxocortisol in glucocorticoid-suppressible aldosteronism.
A radioimmunoassay procedure for the measurement of urinary 18-oxocortisol was developed. The antibody was raised against 18… 
Highly Cited
1983
Highly Cited
1983
Biosynthesis of 18-oxocortisol by aldosterone-producing adrenal tissue.
Aldosterone-biosynthesizing adrenal tissue contains an angular methyl oxidase which converts corticosterone to 18… 
1983
1983
18-oxocortisol, a naturally occurring mineralocorticoid agonist.
Two C-18-oxygenated corticosteroids, 18-hydroxy- and 18-oxocortisol, have recently been isolated from the urine of patients with… 
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