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18-Hydroxydesoxycorticosterone

Known as: 18 Hydroxy 11 Desoxycorticosterone, 18-Hydroxy-11-Desoxycorticosterone, 18 Hydroxydesoxycorticosterone 
An analog of desoxycorticosterone which is substituted by a hydroxyl group at the C-18 position.
National Institutes of Health

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9 relations

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18,19-dihydroxydeoxycorticosterone18-hydroxytetrahydrodeoxycorticosterone
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Multiplexed steroid profiling of gluco- and mineralocorticoids pathways using a liquid chromatography tandem mass spectrometry method
Serum steroid assays are major tools in the clinical evaluation of adrenal disorders. The main adrenal steroids are routinely… 
Highly Cited
1993
Highly Cited
1993
Linkage of 11β-hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat
In Dahl salt-hypertension sensitive (S) and resistant (R) strains fed a high NaCI diet, 11β-hydroxylase polymorphisms cosegregate… 
Highly Cited
1990
Highly Cited
1990
Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism.
A cDNA clone encoding human aldosterone synthase cytochrome P-450 (P-450aldo) has been isolated from a cDNA library derived from… 
Highly Cited
1983
Highly Cited
1983
Adrenocortical hormones, ageing and mental condition: seasonal and circadian rhythms of plasma 18-hydroxy-11-deoxycorticosterone, total and free cortisol and urinary corticosteroids.
The circannual rhythms of plasma 18-hydroxy-11-deoxycorticosterone (18-OH-DOC), total and free cortisol have been documented on a… 
Highly Cited
1982
Highly Cited
1982
Adrenal circadian system in young and elderly human subjects: a comparative study.
Circadian changes in plasma 18-hydroxy-11-deoxycorticosterone (18-OH-DOC), total and unbound cortisol were studied in four groups… 
Review
1976
Review
1976
Adrenocortical factors in hypertension. I. Significance of 18-hydroxy-11-deoxycorticosterone.
  • S. Ulick
  • The American journal of cardiology
  • 1976
  • Corpus ID: 9813471
Low renin essential hypertension and the syndrome of mineralocorticoid excess have two features in common, low plasma renin… 
1976
1976
Structure and mechanism of formation of the two forms of 18-hydroxy-11-deoxycorticosterone.
Abstract 18-Hydroxy-11-deoxycorticosterone (18-OH-DOC) has been observed to exist in two interconvertible forms of markedly… 
Highly Cited
1975
Highly Cited
1975
Adrenal steroidogenesis in the spontaneously hypertensive rat (SHR).
Adrenal vein catheterizations were done in SHR and control rats at different ages during the development of hypertension. All SHR… 
Highly Cited
1975
Highly Cited
1975
Estimation of aldosterone, 11-deoxycorticosterone, 18-hydroxy-11-deoxy-corticosterone, corticosterone, cortisol and 11-deoxycortisol in human plasma by gas-liquid chromatography with electron capture…
A method for determining the plasma concentrations of six major corticosteroids, aldosterone, 18-hydroxy-11-deoxycorticosterone… 
Review
1972
Review
1972
18-Hydroxy-11-deoxycorticosterone (18-OH-DOC) secretion in experimental and human hypertension.
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