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14-thienyl methylene matrine

Known as: YYJ18 compound 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2018
0119652018

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2 relations

Broader (2)

QuinolizidinesThiophenes

Related mentions per year

Related mentions per year

1948-2018
19401960198020002020
14-thienyl methylene matrine
Thiophenes
Quinolizidines

Papers overview

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2018
2018
Design, synthesis and biological evaluation of matrine derivatives as potential anticancer agents.
Using matrine (1) as the lead compound, a series of new 14-(N-substituted-2-pyrrolemethylene) matrine and 14-(N-substituted… (More)
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2017
2017
Matrine reduces the proliferation of A549 cells via the p53/p21/PCNA/eIF4E signaling pathway
The aim of the present study was to investigate how matrine affects the proliferation of A549 human lung adenocarcinoma cells via… (More)
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2016
2016
Matrine-induced autophagy counteracts cell apoptosis via the ERK signaling pathway in osteosarcoma cells.
The aim of the present study was to observe whether autophagy was induced by matrine, and to investigate the role of autophagy in… (More)
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2015
2015
Simultaneous determination of 14-thienyl methylene matrine and matrine in rat plasma by high-performance liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study.
A rapid, sensitive and selective high-performance liquid chromatography-tandem mass spectrometric method (HPLC-MS) has been… (More)
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2014
2014
14-Thienyl methylene matrine (YYJ18), the derivative from matrine, induces apoptosis of human nasopharyngeal carcinoma cells by targeting MAPK and PI3K/Akt pathways in vitro.
BACKGROUND/AIMS Nasopharyngeal carcinoma (NPC) is a distinctive type of head and neck cancer with the highest incidence in South… (More)
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2007
2007
[Inhibition of NF-kappa B activity enhanced apoptosis induced by matrine in hepatocellular carcinoma cells].
OBJECTIVE To investigate the relationship between activation of nuclear factor-kappa gene binding (NF-kappaB) and apoptosis… (More)
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2004
2004
X-ray structural investigation of allomatrine and its N-oxide
For a long time, allomatrine, obtained by the isomerization of matrine [i], was not considered to be a natural base, and only… (More)
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1965
1965
The total syntheses of d,l-matrine and d,l-leontine.
 
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