FAQ

1-pyrroline dehydrogenase activity

Known as: YdcW, ABALDH, gamma-aminobutyraldehyde dehydrogenase activity 
Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+. [MetaCyc:1.5.1.35-RXN]

Topic mentions per year

Topic mentions per year

1992-2013
0119922013

Papers overview

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2014
2014
Structure-based mutational studies of substrate inhibition of betaine aldehyde dehydrogenase BetB from Staphylococcus aureus.
Inhibition of enzyme activity by high concentrations of substrate and/or cofactor is a general phenomenon demonstrated in many… (More)
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2013
2013
Identification and characterization of Klebsiella pneumoniae aldehyde dehydrogenases increasing production of 3-hydroxypropionic acid from glycerol.
Klebsiella pneumoniae produces 3-hydroxypropionic acid (3-HP) from glycerol with oxidation of 3-hydroxypropionaldehyde (3-HPA) to… (More)
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2012
2012
Pathway and enzyme redundancy in putrescine catabolism in Escherichia coli.
Putrescine as the sole carbon source requires a novel catabolic pathway with glutamylated intermediates. Nitrogen limitation does… (More)
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2011
2011
A synthetic metabolic pathway for production of the platform chemical isobutyric acid.
Society currently relies on fossil-based resources for energy and chemical feedstocks. Due to the depletion of oil reserves… (More)
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2007
2007
Crystal structure of lactaldehyde dehydrogenase from Escherichia coli and inferences regarding substrate and cofactor specificity.
Aldehyde dehydrogenases catalyze the oxidation of aldehyde substrates to the corresponding carboxylic acids. Lactaldehyde… (More)
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2005
2005
Identification of Escherichia coli K12 YdcW protein as a gamma-aminobutyraldehyde dehydrogenase.
Gamma-aminobutyraldehyde dehydrogenase (ABALDH) from wild-type E. coli K12 was purified to apparent homogeneity and identified as… (More)
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2004
2004
Crystal structure and kinetics identify Escherichia coli YdcW gene product as a medium-chain aldehyde dehydrogenase.
In the context of a medium-scaled structural genomics program aiming at solving the structures of as many as possible bacterial… (More)
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1999
1999
Aldehyde dehydrogenase from rat intestinal mucosa: purification and characterization of an isozyme with high affinity for gamma-aminobutyraldehyde.
In rat adrenal gland and gastric mucosa putrescine is efficiently oxidized to GABA via gamma-aminobutyraldehyde (ABAL) by action… (More)
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1992
1992
Purification and characterization of bovine brain gamma-aminobutyraldehyde dehydrogenase.
gamma-Aminobutyraldehyde dehydrogenase was purified to homogeneity from bovine brain. The molecular weight of the native enzyme… (More)
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