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1-methylpyrene

 
National Institutes of Health

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Pyrenes

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2018
2018
Analysis and toxicity of 59 PAH in petrogenic and pyrogenic environmental samples including dibenzopyrenes, 7H-benzo[c]fluorene, 5-methylchrysene and 1-methylpyrene.
In this study 59 PAH were analyzed in samples of petrogenic and pyrogenic sources as well as mixed environmental matrices. Among… Expand
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2015
2015
Genotoxicity of 1-methylpyrene and 1-hydroxymethylpyrene in Chinese hamster V79-derived cells expressing both human CYP2E1 and SULT1A1.
1-Methylpyrene (1-MP) is a widespread pollutant that is carcinogenic in animals following metabolic activation. Previous studies… Expand
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2015
2015
Simultaneous Detection of Multiple DNA Adducts in Human Lung Samples by Isotope-Dilution UPLC-MS/MS
Recent studies have demonstrated that various DNA adducts can be detected in human tissues and fluids using liquid chromatography… Expand
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2013
2013
The carcinogen 1-methylpyrene forms benzylic DNA adducts in mouse and rat tissues in vivo via a reactive sulphuric acid ester
Abstract The common polycyclic aromatic hydrocarbon 1-methylpyrene is hepatocarcinogenic in the newborn mouse assay. In vitro… Expand
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2013
2013
Effects of Nereis diversicolor on the transformation of 1-methylpyrene and pyrene: transformation efficiency and identification of phase I and II products.
Transformation of nonsubstituted and alkyl-substituted polycyclic aromatic hydrocarbons (PAHs) by the benthic invertebrate Nereis… Expand
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2008
2008
Time course of hepatic 1-methylpyrene DNA adducts in rats determined by isotope dilution LC-MS/MS and 32P-postlabeling.
The alkylated polycyclic aromatic hydrocarbon 1-methylpyrene is a carcinogen in rodents and has been detected in various… Expand
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2002
2002
Characterization of Micelles of Quaternary Ammonium Surfactants as Reaction Media I: Dodeclytrimethylammonium Bromide and Chloride
Time-resolved fluorescence quenching (TRFQ) and electron paramagnetic resonance (EPR) were employed to characterize micelles of… Expand
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2001
2001
Occurrence and potential adverse effects of semivolatile organic compounds in streambed sediment, United States, 1992-1995.
The occurrence and potential adverse effects of select semivolatile organic compounds (SVOCs) in streambed sediment were assessed… Expand
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1999
1999
Benzylic hydroxylation of 1-methylpyrene and 1-ethylpyrene by human and rat cytochromes P450 individually expressed in V79 Chinese hamster cells.
Alkyl-substituted polycyclic aromatic hydrocarbons may be metabolized to highly reactive benzylic sulfuric acid esters via… Expand
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1987
1987
Methylated derivatives of pyrene and fluorene: evaluation of genotoxicity in the hepatocyte/DNA repair test and tumorigenic activity in newborn mice.
The genotoxicity of 1-methylpyrene, 1,6-dimethylpyrene, 1-methylfluorene, 9-methylfluorene, and 1,9-dimethylfluorene was… Expand
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