1-butanol biosynthetic process

Known as: 1-butanol anabolism, butan-1-ol biosynthetic process, 1-butanol formation 
The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O. [CHEBI:28885, GOC:ecd… Expand
National Institutes of Health

Papers overview

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2018
2018
An oleaginous yeast platform for renewable 1-butanol synthesis based on a heterologous CoA-dependent pathway and an endogenous pathway
BackgroundMicrobial biofuel production provides a promising sustainable alternative to fossil fuels. 1-Butanol is recognized as… Expand
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2017
2017
Leucine zipper-mediated targeting of multi-enzyme cascade reactions to inclusion bodies in Escherichia coli for enhanced production of 1-butanol.
Metabolons in nature have evolved to facilitate more efficient catalysis of multistep reactions through the co-localization of… Expand
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2016
2016
Self-regulated 1-butanol production in Escherichia coli based on the endogenous fermentative control
BackgroundAs a natural fermentation product secreted by Clostridium species, bio-based 1-butanol has attracted great attention… Expand
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2015
2015
Quantitative target analysis and kinetic profiling of acyl-CoAs reveal the rate-limiting step in cyanobacterial 1-butanol production
Cyanobacterial 1-butanol production is an important model system for direct conversion of CO2 to fuels and chemicals… Expand
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2013
2013
Improving biobutanol production in engineered Saccharomyces cerevisiae by manipulation of acetyl-CoA metabolism
Recently, butanols (1-butanol, 2-butanol and iso-butanol) have generated attention as alternative gasoline additives. Butanols… Expand
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Highly Cited
2013
Highly Cited
2013
Transcription factor-based screens and synthetic selections for microbial small-molecule biosynthesis.
Continued advances in metabolic engineering are increasing the number of small molecules being targeted for microbial production… Expand
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Highly Cited
2011
Highly Cited
2011
Driving forces enable high-titer anaerobic 1-butanol synthesis in Escherichia coli.
1-Butanol, an important chemical feedstock and advanced biofuel, is produced by Clostridium species. Various efforts have been… Expand
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2011
2011
Metabolic engineering of Escherichia coli for 1-butanol biosynthesis through the inverted aerobic fatty acid β-oxidation pathway
The basic reactions of the clostridial 1-butanol biosynthesis pathway can be regarded to be the inverted reactions of the fatty… Expand
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2011
2011
Extending carbon chain length of 1-butanol pathway for 1-hexanol synthesis from glucose by engineered Escherichia coli.
An Escherichia coli strain was engineered to synthesize 1-hexanol from glucose by extending the coenzyme A (CoA)-dependent 1… Expand
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