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1,3-diaza-2-oxophenothiazine

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Development of a Vivid FRET System Based on a Highly Emissive dG-dC Analogue Pair.
A new type of Förster Resonance Energy Transfer (FRET) system using highly emissive isomorphic nucleobase analogues is reported… 
2015
2015
Fluorescent Sensor for PH Monitoring Based on ani-Motif- – Switching Aptamer Containing a Tricyclic Cytosine Analogue (tC)
There are cytosine-rich regions in the genome that bind protons with high specificity. Thus protonated C-rich sequence may… 
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2013
2013
Discrimination against major groove adducts by Y-family polymerases of the DinB subfamily.
Y-family DNA polymerases bypass DNA adducts in a process known as translesion synthesis (TLS). Y-family polymerases make contacts… 
2011
2011
Discrimination against the cytosine analog tC by Escherichia coli DNA polymerase IV DinB.
The cytosine analog 1,3-diaza-2-oxophenothiazine (tC) is a fluorescent nucleotide that forms Watson-Crick base pairs with dG. The… 
2010
2010
Mechanisms by which human DNA primase chooses to polymerize a nucleoside triphosphate.
Human DNA primase synthesizes short RNA primers that DNA polymerase alpha then elongates during the initiation of all new DNA… 
2009
2009
Ambivalent incorporation of the fluorescent cytosine analogues tC and tCo by human DNA polymerase alpha and Klenow fragment.
We studied the incorporation of the fluorescent cytidine analogues 1,3-diaza-2-oxophenothiazine (tC) and 1,3-diaza-2… 
2009
2009
Synthesis of a fluorescent 2'3'-dideoxycytosine analog, tCdd.
The pathway leading to the preparation of a novel tricyclic 2'3'-dideoxycytosine analog, tCdd (1) is reported. A protected 2'3… 
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2009
2009
Fluorophore-quencher pair for monitoring protein motion.
A fluorophore/quencher pair capable of detecting conformational changes of DNA-protein complexes is described. The system employs… 
Highly Cited
2007
Highly Cited
2007
Conformational dynamics of DNA polymerase probed with a novel fluorescent DNA base analogue.
DNA polymerases discriminate between correct and incorrect nucleotide substrates during a "nonchemical" step that precedes… 
Highly Cited
2005
Highly Cited
2005
Fluorescent properties of DNA base analogue tC upon incorporation into DNA — negligible influence of neighbouring bases on fluorescence quantum yield
The quantum yield of the fluorescent tricyclic cytosine analogue, 1,3-diaza-2-oxophenothiazine, tC, is high and virtually… 
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