1,3-diaza-2-oxophenothiazine
National Institutes of Health
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A new type of Förster Resonance Energy Transfer (FRET) system using highly emissive isomorphic nucleobase analogues is reported…
There are cytosine-rich regions in the genome that bind protons with high specificity. Thus protonated C-rich sequence may…
Human DNA primase synthesizes short RNA primers that DNA polymerase alpha then elongates during the initiation of all new DNA…
We studied the incorporation of the fluorescent cytidine analogues 1,3-diaza-2-oxophenothiazine (tC) and 1,3-diaza-2…
DNA polymerases discriminate between correct and incorrect nucleotide substrates during a "nonchemical" step that precedes…
The quantum yield of the fluorescent tricyclic cytosine analogue, 1,3-diaza-2-oxophenothiazine, tC, is high and virtually…