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1,1-dichloro-2,2-difluoroethylene

Known as: 1,1-difluoro-2,2-dichloroethylene, DCDFE 
National Institutes of Health

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Related topics

1 relation

Broader (1)

Chlorofluorocarbons

Papers overview

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2005
2005
Effect of β‐naphthoflavone and phenobarbital on the nephrotoxicity of chlorotrifluoroethylene and 1,1‐dichloro‐2,2‐difluoroethylene in the rat
The role of cytochrome P450 activity in the nephrotoxicity of chlorotrifluoroethylene (CTFE) and 1,1‐dichloro‐2,2… 
2000
2000
Bioactivation of selenocysteine Se-conjugates by a highly purified rat renal cysteine conjugate beta-lyase/glutamine transaminase K.
Selenocysteine Se-conjugates have recently been proposed as potential prodrugs to target pharmacologically active selenol… 
1996
1996
Bioactivation of S-(2,2-dihalo-1,1-difluoroethyl)-L-cysteines and S-(trihalovinyl)-L-cysteines by cysteine S-conjugate beta-lyase: indications for formation of both thionoacylating species and…
The covalent binding of reactive intermediates, formed by beta-elimination of cysteine S-conjugates of halogenated alkenes, to… 
Highly Cited
1994
Highly Cited
1994
Evaluation of nephrotoxicity in vitro using a suspension of highly purified porcine proximal tubular cells and characterization of the cells in primary culture.
The nephrotoxic potential of the macrolide immunosuppressants, FK506 and rapamycin, was compared with that of cyclosporin (CsA… 
1994
1994
Evaluation of nephrotoxicity in vitro using a suspension of highly purified porcine proximal tubular cells and characterization of the cells in primary culture.
Proximal tubular cells (PTC) were isolated from porcine kidney by collagenase treatment, subsequently purified on a discontinuous… 
1991
1991
Metabolism of L-cysteine S-conjugates and N-(trideuteroacetyl)-L-cysteine S-conjugates of four fluoroethylenes in the rat. Role of balance of deacetylation and acetylation in relation to the…
1989
1989
Isolated proximal tubular cells from rat kidney as an in vitro model for studies on nephrotoxicity. II. Alpha-methylglucose uptake as a sensitive parameter for mechanistic studies of acute toxicity…
1988
1988
Nephrotoxicity of mercapturic acids of three structurally related 2,2-difluoroethylenes in the rat. Indications for different bioactivation mechanisms.
1987
1987
Nephrotoxicity and hepatotoxicity of 1,1-dichloro-2,2-difluoroethylene in the rat. Indications for differential mechanisms of bioactivation.
1986
1986
METABOLISM OF THE HEPATOTOXIC AND NEPHROTOXIC 1,1-DICHLORO-2,2-DIFLUOROETHYLENE IN THE RAT - INDICATIONS FOR DIFFERENTIAL MECHANISMS OF BIOACTIVATION
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