FAQ

[tyrosine 3-monooxygenase] kinase activity

Known as: STK4, pheochromocytoma tyrosine hydroxylase-associated kinase activity, tyrosine 3-monooxygenase kinase (phosphorylating) activity 
Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase]. [EC:2.7.11.6, MetaCyc:TYROSINE-3… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2017
02420092017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
EBV lymphoproliferative-associated disease and primary cardiac T-cell lymphoma in a STK4 deficient patient
RATIONALE Primary cardiac lymphoma (PLC) is an extremely uncommon malignancy. PCL is more common in secondary immunodeficient… (More)
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2017
2017
Mapping the STK4/Hippo signaling network in prostate cancer cell
Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor… (More)
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2016
2016
RNA-Seq analysis of non-small cell lung cancer in female never-smokers reveals candidate cancer-associated long non-coding RNAs.
We aimed to elucidate the potential mechanisms of long non-coding RNAs (lncRNAs) in the progression of non-small cell lung cancer… (More)
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2016
2016
The Hippo/MST Pathway Member SAV1 Plays a Suppressive Role in Development of the Prehierarchical Follicles in Hen Ovary
The Hippo/MST signaling pathway is a critical player in controlling cell proliferation, self-renewal, differentiation, and… (More)
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2015
2015
Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagy.
The protein LC3 is indispensible for the cellular recycling process of autophagy and plays critical roles during cargo… (More)
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2015
2015
STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) is frequently associated with pathogen infection-induced chronic inflammation. Large numbers of… (More)
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2014
2014
MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo
MicroRNAs (miRNAs) comprise a class of short, non-coding RNAs that regulate protein synthesis through posttranscriptional… (More)
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2014
2014
Spatiotemporal proteomic analyses during pancreas cancer progression identifies serine/threonine stress kinase 4 (STK4) as a novel candidate biomarker for early stage disease.
Pancreas cancer, or pancreatic ductal adenocarcinoma, is the deadliest of solid tumors, with a five-year survival rate of <5… (More)
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2012
2012
The phenotype of human STK4 deficiency.
We describe a novel clinical phenotype associating T- and B-cell lymphopenia, intermittent neutropenia, and atrial septal defects… (More)
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Highly Cited
2009
Highly Cited
2009
Identification of tumor-associated autoantigens for the diagnosis of colorectal cancer in serum using high density protein microarrays.
There is a mounting evidence of the existence of autoantibodies associated to cancer progression. Antibodies are the target of… (More)
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