• Corpus ID: 77699185

Third-degree heart block developing in an HLA-B27-positive individual with a family history of ankylosing spondylitis.

@article{Sp1990ThirddegreeHB,
  title={Third-degree heart block developing in an HLA-B27-positive individual with a family history of ankylosing spondylitis.},
  author={Sahi Sp and Winfield Cr},
  journal={The British journal of clinical practice},
  year={1990},
  volume={44},
  pages={794-795},
  url={https://api.semanticscholar.org/CorpusID:77699185}
}
  • Sahi SpWinfield Cr
  • Published 1 December 1990
  • Medicine
  • The British journal of clinical practice
A case of complete heart block is presented in a patient whose brothers were known to have ankylosing spondylitis. Uveitis and sacro-iliitis are well recognised among HLA-B27-positive siblings of

HLA-B27-Associated Cardiac Disease

An HLA-B27-associated cardiac syndrome is identified that consists of severe cardiac conduction system abnormalities and lone aortic regurgitation; the link between this syndrome and HLA -B27 is almost as strong as the links between ankylosing spondylitis and Hla-B 27.

Cardiac conduction system abnormalities in ankylosing spondylitis: a cross-sectional study

Cardiac conduction abnormalities are common in ankylosing spondyloarthropathies, but not associated with markers of disease activity or specific B27 subtypes, and might indirectly affect morbidity and mortality.