Starch microparticles as vaccine adjuvant
@article{Rydell2005StarchMA, title={Starch microparticles as vaccine adjuvant}, author={Niclas Rydell and Linda Stertman and Ingvar Sjöholm}, journal={Expert Opinion on Drug Delivery}, year={2005}, volume={2}, pages={807 - 828}, url={https://api.semanticscholar.org/CorpusID:23506603} }
This review gives an account of the different starch adjuvants used in immunisation studies and the properties of polyacryl starch microparticles as an oral vaccine adjuvant that induce protective immune responses in mice challenge experiments are summarized.
31 Citations
Raw starch microparticles have immunostimulant activity in mice vaccinated with BCG and challenged with Mycobacterium tuberculosis.
- 2017
Materials Science, Medicine
Bioadhesive delivery systems for mucosal vaccine delivery
- 2010
Medicine
It appears most likely that successful mucosal vaccination will require the addition of vaccine adjuvants for optimal immune responses, particularly if they are to be used in an unprimed population.
Non-ionic surfactant technology for the delivery and administration of sub-unit flu antigens
- 2013
Medicine, Chemistry
This thesis demonstrates that niosomes can be used as delivery systems for peptides and protein sub-unit antigens by providing antigen protection thereby, enhancing vaccine efficacy when administered orally and intramuscularly.
Respiratory nanoparticle-based vaccines and challenges associated with animal models and translation
- 2015
Medicine
Vaccines , Adjuvants , and Delivery Systems for Infectious Diseases
- 2012
Medicine
The best approach for reducing the death and suffering of humans and animals due to viral, bacterial, and parasitic diseases is prevention using effective vaccines, and the technology of vaccine development and production has not changedSignificantly over the years.
Formulation design considerations for oral vaccines.
- 2011
Medicine
The options available for consideration when building effective oral particulate vaccines are established and it is established that formulating particulates with inherent adjuvant properties can offer advantages.
Nanotechnology-driven advances in intranasal vaccine delivery systems against infectious diseases
- 2025
Medicine, Materials Science
This review elucidates the potential and current status of intranasal delivery systems, while also serving as a reference point for the future development of intranasal vaccines.
167 References
Starch Microparticles as Oral Vaccine Adjuvant: Antigen-dependent Uptake in Mouse Intestinal Mucosa
- 2004
Medicine
The qualitative difference in uptake could be of importance for the development of an immune response as the cytokine and chemokine microenvironment during antigen presentation will decide the differentiation of the immune response induced.
Poly(lactide-co-glycolide) microparticles for the development of single-dose controlled-release vaccines.
- 1998
Medicine, Materials Science
Extracellular Antigens from Salmonella enteritidis Induce Effective Immune Response in Mice after Oral Vaccination
- 2002
Biology, Medicine
The delayed-type hypersensitivity test, as a measure of the cellular response, showed a significant increase in ear thickness in all the immunized groups, except for the group that received free antigen orally, compared to the nonimmunized group.