Durable Resolution of Severe Psoriasis in a Patient Treated with Pentostatin for Hairy Cell Leukemia: A Case Report
@article{Alsuliman2017DurableRO, title={Durable Resolution of Severe Psoriasis in a Patient Treated with Pentostatin for Hairy Cell Leukemia: A Case Report}, author={Tamim Alsuliman and Kaiss Lassoued and Maifa Belghoul and Karima Debbache and Bachra Choufi}, journal={Dermatology and Therapy}, year={2017}, volume={8}, pages={165 - 169}, url={https://api.semanticscholar.org/CorpusID:3509453} }
It is believed that adenosine analogues constitute a promising therapeutic option for moderate to severe psoriasis, especially for severe and refractory psOriasis, as well as for patients with adjacent lymphoid malignancies.
3 Citations
Purinergic Signaling and Inflammasome Activation in Psoriasis Pathogenesis
- 2021
Medicine, Biology
It is envisage that intracellular ATP, released by damaged cells, may play a role in triggering the inflammatory response underlying the pathogenesis of the disease by activating the inflammasome, opening the possibility to target single molecular actors of the purinome to develop new psoriasis treatments.
高效液相色谱-串联质谱法同时测定发酵液中喷司他丁和2'-氨基-2'-脱氧腺苷
- 2021
Biology
The HPLC-MS/MS method for the determination of the pentostatin and 2'-amino-2'-deoxyadenosine in fermentation broth offered the advantages of small sampling volume, strong maneuverability, good stability, and high sensitivity.
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Medicine
Evidence for sustained therapeutic efficacy of 2-CDA in chronic plaque psoriasis in the absence of severe side effects except asymptomatic lymphopenia is provided.
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Medicine
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Medicine
The intravenous administration of the drug ensures compliance in a patient group in which oral therapy is difficult to monitor, and future studies, including treatment of children newly diagnosed with high-risk chronic GVHD, are warranted.
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Medicine
Mycosis fungoides is the most common variant of cutaneous T-cell lymphomas among the EORTC-ISCL classification and their skin lesions can be well controlled using skin-directed therapies.
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Medicine
Treatment with cladribine tablets significantly reduced relapse rates, the risk of disability progression, and MRI measures of disease activity at 96 weeks, and the benefits need to be weighed against the risks.
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- 2015
Medicine
In vitro cladribine exposure induces a sustained anti-inflammatory shift in the cytokine profile of surviving peripheral blood mononuclear cells, which might contribute tocladribine’s beneficial effects in the treatment of multiple sclerosis.
Systemic treatment for psoriasis and malignancies: A real risk?
- 2017
Medicine
A 12-year retrospective study investigating the development of malignancies in psoriasis patients attending the Dermatological Clinic of the University Federico II of Naples undergoing conventional or biologic systemic treatment results are in line with those of Magnano et al. (2017), showing that biologic treatment seemed not to increase malignancy risk in psoriatic patients.
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Medicine
The case of a 58-year-old immunocompetent man with a 18-year history of plaque psoriasis who develops ophthalmic HZ during treatment with adalimumab is reported to enrich the literature and to highlight the increased risk of HZ infections in patient on anti-TNF-α therapy.