• Corpus ID: 51686967

Clinicopathological studies on gentamicin toxicity in White Leghorn commercial layers.

@article{NajamUlIslam2011ClinicopathologicalSO,
  title={Clinicopathological studies on gentamicin toxicity in White Leghorn commercial layers.},
  author={Najam-Ul-Islam and Misal Khan and Muhammad Kashif Saleemi and Ahrar Khan and Sheraz Ahmed Bhatti and Muhammad Murtaza Yousaf and Zahoor-ul-Hassan},
  journal={Pakistan Veterinary Journal},
  year={2011},
  volume={31},
  pages={305-308},
  url={https://api.semanticscholar.org/CorpusID:51686967}
}
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20 References

Gentamicin nephrotoxicity in humans and animals: some recent research.

Evaluation of Efficacy of Vitamin E and N-Acetyl Cysteine in Gentamicin-Induced Nephrotoxicity in Rats

Treatment and posttreatment with vitamin E and NAC significantly restored renal functions, reduced lipid peroxidation, enhanced reduced glutathione level, and restored the biochemical parameters in gentamicin-induced nephrotoxicity.

Pharmacokinetics, nephrotoxicosis, and in vitro antibacterial activity associated with single versus multiple (three times) daily gentamicin treatments in horses.

Evidence is provided to support the use of once-daily gentamicin treatment in adult horses that was not induced with either dosage regimen, and postantibiotic effects were prolonged with a higher Gentamicin concentration.

Depletion of gentamicin and its major components from various tissues of turkeys.

Results suggest that tissue depletion profiles of the 3 major components of gentamicin differ from each other, and withdrawal time, therefore, may depend on the ratio of the components in the pharmaceutical preparation used.

Pathological and Biochemical Effects of Intramuscular Gentamicin Administration in Chickens

Gentamicin administration resulted in a significant decrease in serum albumin and a significant increase in urea nitrogen and creatinine concentrations and microscopically acute tubular necrosis was observed in the kidneys and fatty change of hepatocytes in the liver.

Toxicity of gentamicin in red-tailed hawks.

Increased numbers of cytoplasmic lysosomes, many of which contained myelin figures, in renal epithelial cells were seen at the ultrastructural level, and all birds given 20 mg/kg died.

Gentamicin-associated acute kidney injury.

It is shown that gentamicin-associated AKI remains a common and potentially serious clinical problem and there is a strong correlation between RIFLE class and in-hospital mortality.

Protective effects of nigella sativa against gentamicin-induced nephrotoxicity in rats.

Assessment of gentamicin-induced nephrotoxicity in rats treated with low doses of ibuprofen and diclofenac sodium.

It is demonstrated that gentamicin nephrotoxicity was potentiated after the long (27 days) but not after the short (5 days) period of treatment with ibuprofen and diclofenac sodium, and prolonged administration of non-steroidal anti-inflammatory drugs should be considered as a risk factor that may increase the neph rotoxic potential of Gentamicin.

Pathological effects of gentamicin administered intramuscularly to day-old broiler chicks.