• Corpus ID: 39599472

Antirheumatic drugs, the ESR, and the hypohistidinemia of rheumatoid arthritis.

@article{Gerber1977AntirheumaticDT,
  title={Antirheumatic drugs, the ESR, and the hypohistidinemia of rheumatoid arthritis.},
  author={Donald A. Gerber},
  journal={The Journal of rheumatology},
  year={1977},
  volume={4 1},
  pages={
          40-5
        },
  url={https://api.semanticscholar.org/CorpusID:39599472}
}
In patients with RA receiving various combinations of aspirin, prednisone, and gold, the regression lines relating the serum histidine concentrations to the sedimentation rates had similar slopes but different elevations compared to patients receiving no anti-inflammatory drugs, consistent with the hypothesis that hypohistidinemia contributes to the pathogenesis of RA.

The effect of drugs on serum histidine levels in rheumatoid arthritis

SummaryGroups of 15 patients with active rheumatoid arthritis were treated for 24 weeks with zinc sulphate, trien, captopril, clozic in two doses or a combination of d-penicillamine and

Biochemical indices of response to hydroxychloroquine and sodium aurothiomalate in rheumatoid arthritis.

Correlations obtained with gold were more frequent and of a higher level of significance than those obtained with hydroxychloroquine at the doses the authors studied, lending support to the use of correlation matrices as a screening test for potential long-term antirheumatoid activity of drugs in man.