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dCas9 Targeted Chromatin and Histone Enrichment for Mass Spectrometry (Catchet-MS) Identifies IKZF1 as a Novel Drug-Able Target for HIV-1 Latency Reversal

The drug iberdomide, which targets IKZF1 for degradation, is found to be a clinically advanced novel LRA that reverses latency in latent ex vivo HIV-1 infected primary CD4+ T cells and in cells isolated from virally suppressed HIV- 1 infected participants.
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Effects of neutron irradiation on glass ceramics as pressure-less joining materials for SiC based components for nuclear applications

Abstract This paper reports on the microstructure and properties of two glass–ceramics based on SiO 2 –Al 2 O 3 –MgO (SAMg) and SiO 2 –Al 2 O 3 –Y 2 O 3 (SAY), which have been designed to be used as…
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Design, construction and operation of a graphite irradiation creep facility

Abstract Representative irradiated graphite properties are essential for the successful design, licensing and long term operation of a graphite moderated reactor. These properties are acquired from…
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Influence of neutron irradiation on the microstructure of nuclear graphite: An X-ray diffraction study

Abstract Neutron irradiation effects on the microstructure of nuclear graphite have been investigated by X-ray diffraction on virgin and low doses ( ∼ 1.3 and ∼ 2.2 dpa), high temperature (750° C)…
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