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Safety and long-term efficacy of fractional CO2 laser treatment in women suffering from genitourinary syndrome of menopause.

Fractional microablative CO2 laser treatment was associated with an improvement in symptoms of GSM and sexual function and scores on measures of sexual function, dyspareunia, and bothersomeness of sexual issues were improved from pre-treatment to long-term follow-up.
PubMed (opens in a new tab)

Use of Platelet-rich Plasma for Vulvovaginal Autoimmune Conditions Like Lichen Sclerosus

It is hypothesized that PRP presents a potential alternative to topical steroids for treatment of vulvovaginal autoimmune conditions such as LS, and a larger pilot and/or randomized controlled trial study is required to evaluate this finding further.
Wolters Kluwer (opens in a new tab)

In vitro evaluation of biocompatibility and degradation of human blood-derived scaffolds by seeding of mouse embryo fibroblasts

It is found that scaffold demonstrated in vitro biocompatibility, cell adhesion, and controlled biodegradation, supporting its clinical application in tissue engineering.
Publisher (opens in a new tab)

Platelet-Rich Plasma and Fractional CO2 Laser Therapy to Reduce Surgical Intervention for Symptomatic Vaginal Mesh-Related Complications

Platelet-rich plasma and CO2 laser treatments allowed most women to avoid surgery, improving bladder, bowel, sexual function and vaginal atrophy and these alternatives may expand treatment options for mesh complications.
Springer Nature (opens in a new tab)

Fractional CO2 laser for treatment of stress urinary incontinence

This study suggests that fractional CO2 laser is a safe, feasible, and beneficial treatment for SUI and may have a role as a minimally-invasive alternative to surgical management.
PubMed (opens in a new tab)

Application of Platelet-Rich Plasma in Gynaecologic Disorders: A Scoping Review

PRP improved symptoms and QoL in several conditions, particularly VLS and SD, and was generally well tolerated with minor adverse effects, showing promise as a minimally invasive therapy for certain gynaecological conditions.
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The Investigation of Percutaneous Tibial Nerve Stimulation (PTNS) as a Minimally Invasive, Non-Surgical, Non-Hormonal Treatment for Overactive Bladder Symptoms

The results suggest thatPTNS may be a second-line treatment for patients with OAB not responding to conservative management or for patients aiming to avoid surgical approaches, and support that PTNS is a minimally invasive, non-surgical,non-hormonal, and effective treatment for OAB.
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In Vivo investigation of xenotransplanted human blood-derived scaffold into mice as a biodegradable construct for improvement of pelvic floor repair

The novel human blood-derived scaffold demonstrated biodegradation and high biocompatibility, and Suturing the scaffold on the abdominal wall or back muscle effectively improves clinical symptoms, while further improvements are needed for its clinical application.
PDF (opens in a new tab)
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