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Effect of Metformin Intervention during Pregnancy on the Gestational Diabetes Mellitus in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis

Effectiveness analysis demonstrated that, in total, there was no significant availability of metformin on GDM in PCOS in contrast to placebo, though more multicenters RCTs still need to be investigated.
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Thrombopoietin receptor agonists for prevention and treatment of chemotherapy-induced thrombocytopenia in patients with solid tumours.

There is not enough evidence to determine whether TPO-RAs reduce the number of patients with at least one severe/life-threatening bleeding episode of any severity, and the overall risk of bias as high as it is as high for number and severity of bleeding episodes is judged.
PubMed (opens in a new tab)

Studies of cardiovascular risk factors in polycystic ovary syndrome patients combined with subclinical hypothyroidism

The PCOS patients combined with SCH have higher risk of cardiovascular risk factors than in controls or in patients with PCOS.
Taylor & Francis (opens in a new tab)

Preservation of Fertility in Females Treated for Cancer

This article reviews the available fertility preservation methods in women, and the related issues including normal physiology of the ovary, effect of anticancer therapy on fertility, role of the oncologist and ethics.
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The utility of human fallopian tube mucosa as a novel source of multipotent stem cells for the treatment of autologous reproductive tract injury

HFMMSCs demonstrated stronger proliferative capacity and superior secretion of growth factors and immunomodulatory cytokines than hFTMSCs, making the former a better source of stem cells for the treatment of autologous reproductive tract injury.
Springer Nature (opens in a new tab)

Abnormal expression of microRNA-575 leads to missed abortion through regulating apoptosis and angiogenesis

Numerous microRNA (miR) are important for placental development and function. miR-575 has been demonstrated to be upregulated in maternal placenta in patients who have experienced a miscarriage. The…
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Expression of apoptosis-related genes in the endometrium of polycystic ovary syndrome patients during the window of implantation.

The decrease in cell apoptosis during the window of implantation in polycystic ovary syndrome patients may be one of the causes of the reduced endometrial receptivity.
PubMed (opens in a new tab)

Vascular endothelial growth factor (VEGF) targeting therapy for persistent, recurrent, or metastatic cervical cancer.

Assessment of the benefits and harms of VEGF targeting agents in the management of persistent, recurrent, or metastatic cervical cancer found very uncertain results for the incidences of specific adverse events, including gastrointestinal perforations or fistulae.
PubMed (opens in a new tab)

Application of SonoVue combined with three-dimensional color power angiography in the diagnosis and prognosis evaluation of intrauterine adhesion.

3D-CPA can indirectly diagnose IUA, and may play an important role in prognosis assessment, and the accuracy, sensitivity, and specificity were evaluated between 3D-TVS and hysteroscopy.
PubMed (opens in a new tab)

Expression of placenta-specific 8 in human oocytes, embryos, and models of in vitro implantation.

The data have demonstrated for the first time that human oocytes and preimplantation embryos express PLAC8 and that the intracellular distribution ofPLAC8 protein is dynamic and regulated in an implantation-dependent manner, which indicates that PLac8 plays a potential role in embryo development and implantation.
PubMed (opens in a new tab)
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