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S-SELeCT: A Human-Evolved Serine Integrase System for Efficient Large-Cargo Genome Integration

These are the first serine integrase enzymes that have been evolved fully in human cells, and the first to recognize an endogenous symmetric non-pseudosite – the first true human serine integrase attachment site.
PubMed (opens in a new tab)

GENE EDITING METHOD USING VIRUS

Development of a high-yield Rabbit line for enhanced animal pharming

This work successfully generated knock-in founder Rabbits using CRISPR/Cas9-mediated knock-in technology, augmented by the homology-directed repair (HDR)-promoting small molecule RS-1, demonstrating a promising strategy to enhance recombinant protein production in Rabbit pharming.
Springer Nature (opens in a new tab)
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