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Teplizumab in Stage 2 Type 1 Diabetes: Clinical Practice Experience on Feasibility in 3 Adult Patients.

The first Italian experience with teplizumab administered under a compassionate use programme for adults with Stage 2 type 1 diabetes (T1D) proved feasible and safe in a real-life academic context, consistent with pivotal trial data.
PubMed (opens in a new tab)

Disrupted Osteoblastogenesis and Mitochondrial Remodeling in MSCs from Patients with Cushing’s Syndrome

Springer Nature (opens in a new tab)

Role of 11β-Hydroxysteroid Dehydrogenase and Mineralocorticoid Receptor on Alzheimer’s Disease Onset: A Systematic Review

11β-HSD1’s role in AD presents a promising therapeutic target, but further studies are required to fully understand its potential in managing the disease.
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Circulating Neuronal Exosome Cargo as Biomarkers of Neuroplasticity in Cushing’s Syndrome

The findings support the following: (i) patients with Cushing’s syndrome may exhibit a putative dysregulation of neurogenesis that could underlie the early-onset impairment of affective and cognitive functions; (ii) the exosomal cargo may represent a potential biomarker for monitoring functional and dysfunctional neuroplasticity processes in adult humans.
Springer Nature (opens in a new tab)
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