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Disease‐Derived Tau Seeds Induce Aggregation and Pathway Disruptions in a Cellular Model

A tau seeding model without overexpression is developed, enabling broader studies of tau interactions, toxicity, and therapeutic interventions in any cell‐type.
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Sequential accumulation of phosphorylated tau species in early Alzheimer's disease

The aim of this study was to perform a detailed proteomic and neuropathological study of pTau accumulation in early AD.
Wiley (opens in a new tab)

Role of Oligodendrocyte Lineage Cells in Multiple System Atrophy

The up-to-date knowledge of human oligodendrocyte lineage cells and their association with α-synuclein is reviewed, and the postulated mechanisms of how oligod endodendrogliopathy develops are discussed, including the potential origins of the toxic seeds of α- synuclein and the possible networks through which oligod Endodermopathy induces neuronal loss.
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