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zosuquidar trihydrochloride

Known as: (2R)-anti-5-(3-(4-(10,11-difluoromethanodibenzo-suber-5-yl)piperazin-1-yl)2-hydroxypropoxy)quinoline trihydrochloride, (R)-4-((1aR,6R,10bS)-1,2-Difluoro-1,1a,6,10b-tetrahydrodibenzo(a,e)cyclopropa(c)cycloheptan-6-yl)-alpha-((5-quinoloyloxy)methyl)-1-piperazineethanol, Trihydrochloride 
A difluorocyclopropyl quinoline. Zosuquidar trihydrochloride binds with high affinity to P-glycoprotein and inhibits P-glycoprotein-mediated… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Significance Two-dimensional (2D) polyaniline (PANI) has been realized for the first time, to our knowledge, by direct solid… Expand
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Highly Cited
2007
Highly Cited
2007
The serine/threonine kinase Akt is a downstream target of dopamine receptor signaling that is inhibited/dephosphorylated in… Expand
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Highly Cited
2006
Highly Cited
2006
Abstract: Background/Aim: Biliary epithelial cells possess an innate immune system consisting of Toll‐like receptors (TLRs… Expand
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Highly Cited
2004
Highly Cited
2004
Aripiprazole,7-(4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyloxy)-3,4-dihydro-carbostycil (OPC-14597), a novel atypical… Expand
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Highly Cited
2003
Highly Cited
2003
The adequate distribution of STI-571 (Gleevec) to the central nervous system (CNS) is critical for its effective use in CNS… Expand
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Highly Cited
1997
Highly Cited
1997
The distribution of 5-HT1A receptors was examined in the post-mortem human brain using whole hemisphere autoradiography and the… Expand
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Highly Cited
1997
Highly Cited
1997
The pharmacological properties of a novel selective 5-hydroxytryptamine1A (5-HT1A) receptor antagonist, NAD-299 [(R)-3-N,N… Expand
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Highly Cited
1995
Highly Cited
1995
WAY-100635 (N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2- pyridinyl)cyclohexanecarboxamide trihydrochloride) is an achiral… Expand
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Highly Cited
1981
Highly Cited
1981
Sir: In testing the activity of culture filtrates to inhibit focus formation of chicken fibroblasts by Rous sarcoma virus, an… Expand
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Highly Cited
1978
Highly Cited
1978
The synthesis and the characterization of a number of diacridines connected through the 9-amino position of the acridine rings by… Expand
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