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zofenopril

Known as: L-Proline, 1-(3-(benzoylthio)-2-methyl-1-oxopropyl)-4-(phenylthio)-, (1(R*),2alpha,4alpha)- 
A sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, zofenopril is hydrolyzed in vivo into its… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (3)

Angiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsCaptopril

Narrower (3)

SQ 26991ZOFENOPRIL CALCIUMZofenil
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Serum cholesterol levels on admission and survival in patients with acute myocardial infarction treated with zofenopril: a post hoc analysis of the Survival of Myocardial Infarction Long‐term…
To evaluate the clinical efficacy of early angiotensin‐converting enzyme (ACE) inhibition by zofenopril in patients with anterior… 
2007
2007
Antihypertensive efficacy of zofenopril plus hydrochlorothiazide fixed combination for treatment in metabolic syndrome
This study was undertaken to compare the antihypertensive efficacy of zofenopril 30 mg + hydrochlorothiazide 12.5 mg fixed… 
2004
2004
Dietary sodium restriction specifically potentiates left ventricular ACE inhibition by zofenopril, and is associated with attenuated hypertrophic response in rats with myocardial infarction
Introduction In patients with myocardial infarction (MI)-induced heart failure, angiotensin-converting enzyme (ACE) inhibitors… 
2004
2004
Diverse effects of Ace inhibitors and angiotensin II receptor antagonists on prevention of cardiac hypertrophy and collagen distribution in spontaneously hypertensive rats.
1997
1997
The effects of atenolol and zofenopril on plasma atrial natriuretic peptide are due to their interactions with target organ damage of essential hypertensive patients
The effects of 10 weeks of treatment with atenolol (n = 9) or the converting enzyme inhibitor zofenopril (n = 25) on plasma… 
1997
1997
The time course of left ventricular remodeling after acute myocardial infarction.
Highly Cited
1991
Highly Cited
1991
Angiotensin Converting Enzyme Inhibition in Heart, Kidney, and Serum Studied Ex Vivo after Administration of Zofenopril, Captopril, and Lisinopril
Summary: Angiotensin converting enzyme inhibition in heart, kidney, and serum were studied ex vivo after oral administration of… 
1991
1991
Converting enzyme inhibition after experimental myocardial infarction in rats: comparative study between spirapril and zofenopril.
STUDY OBJECTIVE The aim was to compare the effects of two novel angiotensin converting enzyme (ACE) inhibitors, spirapril and… 
1991
1991
Different effects of captopril and other angiotensin converting enzyme inhibitors on cardiovascular preparations.
1990
1990
The effects of oral pretreatment with zofenopril, an angiotensin-converting enzyme inhibitor, on early reperfusion and subsequent electrophysiologic stability in the pig
SummaryThe effects of oral zofenopril pretreatment were investigated in a chronic closed-chest pig model of ischemia and… 
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