zacopride

Known as: 4-amino-5-iodo-2-methoxy-N-(1-azabicyclo(2.2.2)oct-3-yl)benzamide, 4-amino-N-(1-azabicyclo(2,2,2)oct-3-yl)-5-chloro-2-methoxybenzamide-2-butenedioate, iodozacopride 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2016
0102019872016

Papers overview

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1992
1992
The effect of the selective 5-HT3 receptor antagonist, zacopride, was assessed in male Sprague-Dawley rats in free choice (6… (More)
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1992
1992
Substitution of the chlorine atom by a radio-iodine in position 5 in the zacopride molecule yielded [125I]iodo-zacopride that… (More)
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1992
1992
The interaction of R(+)- and S(-)zacopride (0.00001-10 mg/kg i.p.) with parachlorophenylalanine (PCPA, 3 day treatment 100 mg/kg… (More)
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1991
1991
The effects of the optical isomers of zacopride were assessed in mice in a fully automated two-compartment light/dark apparatus… (More)
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1990
1990
The distribution of 5-HT3 receptor sites was examined in rat brain by autoradiography using 3H-enantiomers of zacopride. The (S… (More)
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1989
1989
The antiemetic activity of zacopride against a variety of emetogenic agents has been determined in dogs. Zacopride was highly… (More)
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1988
1988
Zacopride, a substituted benzamide derivative, was compared with diazepam in three models of experimental or provoked anxiety… (More)
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1988
1988
[3H]Zacopride displayed saturable binding to homogenates of the rat entorhinal cortex as measured by the inclusion of the 5-HT3… (More)
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1988
1988
Cisplatin administered by either the intravenous (i.v.) or intra-cerebroventricular (i.c.v.) route produced emesis in cats. The… (More)
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1988
1988
The substituted benzamide derivative zacopride was found to antagonize competitively the effects of 5-hydroxytryptamine (5-HT) on… (More)
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