yohimbine

Known as: Johimbin, 17alpha-Hydroxyyohimban-16alpha-carboxylic acid methyl ester, Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16alpha,17alpha)- 
A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Previous studies have shown that orexin-1/hypocretin-1 receptors play a role in self-administration and cue-induced reinstatement… (More)
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Highly Cited
2007
Highly Cited
2007
Yohimbine is an alpha-2 adrenoreceptor antagonist that provokes stress- and anxiety-like responses in both humans and laboratory… (More)
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Highly Cited
2006
Highly Cited
2006
The major problem in treating excessive eating is high rates of relapse to maladaptive eating habits during diet treatments; this… (More)
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Highly Cited
2006
Highly Cited
2006
Stress and drug-associated cues can trigger drug desire and relapse in abstinent cocaine users. Although the role of these two… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Brain noradrenaline is involved in footshock stress-induced reinstatement of drug seeking in a rat relapse model. We… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Consistent with many studies demonstrating enhanced reactivity of the sympathetic nervous system in posttraumatic… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND We have previously reported an increase in symptoms of anxiety in patients with posttraumatic stress disorder (PTSD… (More)
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Highly Cited
1985
Highly Cited
1985
A novel test for the selective identification of anxiolytic and anxiogenic drug effects in the rat is described, using an… (More)
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Highly Cited
1984
Highly Cited
1984
Yohimbine, an alpha 2-adrenergic receptor antagonist that increases noradrenergic function, was administered to 20 healthy… (More)
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Highly Cited
1983
Highly Cited
1983
Yohimbine (30 mg) produced significant increases in subjective anxiety, autonomic symptoms, blood pressure, and plasma 3-methoxy… (More)
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