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yohimbine

Known as: Johimbin, 17alpha-Hydroxyyohimban-16alpha-carboxylic acid methyl ester, Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16alpha,17alpha)- 
A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Astrocytic energy demand is stimulated by K+ and glutamate uptake, signaling processes, responses to neurotransmitters, Ca2… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Brain noradrenaline is involved in footshock stress-induced reinstatement of drug seeking in a rat relapse model. We… Expand
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Review
2000
Review
2000
Concurrent use of herbs may mimic, magnify, or oppose the effect of drugs. Plausible cases of herb-drug interactions include… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Consistent with many studies demonstrating enhanced reactivity of the sympathetic nervous system in posttraumatic… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND We have previously reported an increase in symptoms of anxiety in patients with posttraumatic stress disorder (PTSD… Expand
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Highly Cited
1992
Highly Cited
1992
Tramadol hydrochloride produced dose-related antinociception in mouse abdominal constriction [ED50 = 1.9 (1.2-2.6) mg/kg i.p… Expand
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Highly Cited
1985
Highly Cited
1985
A novel test for the selective identification of anxiolytic and anxiogenic drug effects in the rat is described, using an… Expand
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Highly Cited
1984
Highly Cited
1984
Yohimbine, an alpha 2-adrenergic receptor antagonist that increases noradrenergic function, was administered to 20 healthy… Expand
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Highly Cited
1983
Highly Cited
1983
Yohimbine (30 mg) produced significant increases in subjective anxiety, autonomic symptoms, blood pressure, and plasma 3-methoxy… Expand
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Highly Cited
1980
Highly Cited
1980
  • S. Langer
  • Pharmacological reviews
  • 1980
  • Corpus ID: 22813919
During norepinephrine release elecited by the arrival of nerve impulses, the neurotransmitter interacts with specific receptors… Expand
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