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withanolide D

Known as: (4 beta,5 beta,6 beta,22R)-5,6-epoxy-4,20,22-trihydroxy-1-oxoergosta- 2,24-dien-26-oic acid, delta-lactone, 5,6-epoxy-4,20,22-trihydroxy-1-oxoergosta-2,24-dien-26-oic acid delta-lactone 
 
National Institutes of Health

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Withanolides

Papers overview

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2019
2019
In vitro study of Withanolide D toxicity on goat preantral follicles and its effects on the cell cycle.
The Withanolide D is a chemotherapeutic potential against the human tumor cell. However, there is no report on the effect of this… Expand
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2018
2018
Withaferin A and Withanolide D Analogues with Dual Heat-Shock-Inducing and Cytotoxic Activities: Semisynthesis and Biological Evaluation.
Withanolides constitute a valuable class of bioactive natural products because some members of the class are known to exhibit… Expand
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2018
2018
Withania Somnifera: A New Approach To Cancer
Cancer is a hyper proliferative disorder characterized by the abnormal proliferation of cells that invades into the adjacent… Expand
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2017
2017
Withanolide D Exhibits Similar Cytostatic Effect in Drug-Resistant and Drug-Sensitive Multiple Myeloma Cells
In spite of recent therapeutic advances, multiple myeloma (MM) remains a malignancy with very low curability. This has been… Expand
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2012
2012
Bak Compensated for Bax in p53-null Cells to Release Cytochrome c for the Initiation of Mitochondrial Signaling during Withanolide D-Induced Apoptosis
The goal of cancer chemotherapy to induce multi-directional apoptosis as targeting a single pathway is unable to decrease all the… Expand
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Review
2012
Review
2012
Withanolide D, carrying the baton of Indian rasayana herb as a lead candidate of antileukemic agent in modern medicine.
During cancer, immune system gets suppressed due to developing malignancy and anticancer drugs used. Therefore, an ideal… Expand
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2009
2009
Metabolic clustering of a core collection of Indian ginseng Withania somnifera Dunal through DNA, isoenzyme, polypeptide and withanolide profile diversity.
Withania somnifera is one of the most important medicinal plants of Ayurveda and finds extensive uses in Indian traditional… Expand
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Highly Cited
2006
Highly Cited
2006
Changes in morphological phenotypes and withanolide composition of Ri-transformed roots of Withania somnifera
Developmental variability was introduced into Withania somnifera using genetic transformation by Agrobacterium rhizogenes, with… Expand
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