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withanolide D
Known as:
(4 beta,5 beta,6 beta,22R)-5,6-epoxy-4,20,22-trihydroxy-1-oxoergosta- 2,24-dien-26-oic acid, delta-lactone
, 5,6-epoxy-4,20,22-trihydroxy-1-oxoergosta-2,24-dien-26-oic acid delta-lactone
National Institutes of Health
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Withanolides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Withanolide D Enhances Radiosensitivity of Human Cancer Cells by Inhibiting DNA Damage Non-homologous End Joining Repair Pathway
J. Lacombe
,
Titouan Cretignier
,
+5 authors
F. Zenhausern
Frontiers in Oncology
2019
Corpus ID: 210039604
Along with surgery and chemotherapy, radiation therapy (RT) is an important modality in cancer treatment, and the development of…
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2019
2019
In vitro study of Withanolide D toxicity on goat preantral follicles and its effects on the cell cycle.
D. Guerreiro
,
L. F. de Lima
,
+7 authors
Ana Paula Ribeiro Rodrigues
Reproductive toxicology
2019
Corpus ID: 58641593
The Withanolide D is a chemotherapeutic potential against the human tumor cell. However, there is no report on the effect of this…
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2018
2018
Withaferin A and Withanolide D Analogues with Dual Heat-Shock-Inducing and Cytotoxic Activities: Semisynthesis and Biological Evaluation.
E. Wijeratne
,
M. C. F. Oliveira
,
+6 authors
A. Gunatilaka
Journal of natural products
2018
Corpus ID: 3869860
Withanolides constitute a valuable class of bioactive natural products because some members of the class are known to exhibit…
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2017
2017
Withanolide D Exhibits Similar Cytostatic Effect in Drug-Resistant and Drug-Sensitive Multiple Myeloma Cells
M. Issa
,
E. Wijeratne
,
A. Gunatilaka
,
M. Cuendet
Front. Pharmacol.
2017
Corpus ID: 8438300
In spite of recent therapeutic advances, multiple myeloma (MM) remains a malignancy with very low curability. This has been…
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2012
2012
Bak Compensated for Bax in p53-null Cells to Release Cytochrome c for the Initiation of Mitochondrial Signaling during Withanolide D-Induced Apoptosis
S. Mondal
,
K. Bhattacharya
,
Asish Mallick
,
R. Sangwan
,
C. Mandal
PloS one
2012
Corpus ID: 1041503
The goal of cancer chemotherapy to induce multi-directional apoptosis as targeting a single pathway is unable to decrease all the…
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Review
2012
Review
2012
Withanolide D, carrying the baton of Indian rasayana herb as a lead candidate of antileukemic agent in modern medicine.
S. Mondal
,
S. Roy
,
+4 authors
C. Mandal
Advances in experimental medicine and biology
2012
Corpus ID: 21937968
During cancer, immune system gets suppressed due to developing malignancy and anticancer drugs used. Therefore, an ideal…
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Highly Cited
2009
Highly Cited
2009
Metabolic clustering of a core collection of Indian ginseng Withania somnifera Dunal through DNA, isoenzyme, polypeptide and withanolide profile diversity.
N. D. Chaurasiya
,
R. Sangwan
,
L. N. Misra
,
R. Tuli
,
N. Sangwan
Fitoterapia
2009
Corpus ID: 35337319
Withania somnifera is one of the most important medicinal plants of Ayurveda and finds extensive uses in Indian traditional…
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Highly Cited
2006
Highly Cited
2006
Changes in morphological phenotypes and withanolide composition of Ri-transformed roots of Withania somnifera
M. Bandyopadhyay
,
S. Jha
,
D. Tepfer
Plant Cell Reports
2006
Corpus ID: 25502662
Developmental variability was introduced into Withania somnifera using genetic transformation by Agrobacterium rhizogenes, with…
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