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vitamin K1 oxide

Known as: phylloquinone epoxide, vitamin K1 epoxide, vitamin K1 2,3-epoxide 
 
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Vitamin K epoxide reductase (VKOR) sustains blood coagulation by reducing vitamin K epoxide to the hydroquinone, an essential… Expand
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Review
2006
Review
2006
Vitamin K epoxide, a by-product of the carboxylation of blood coagulation factors, is reduced to vitamin K by an enzymatic system… Expand
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Highly Cited
2005
Highly Cited
2005
The gene encoding vitamin K epoxide reductase complex subunit 1 (VKORC1), a component of the enzyme that is the therapeutic… Expand
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Highly Cited
2005
Highly Cited
2005
A warfarin‐resistant strain and a warfarin‐susceptible strain of wild rats (Rattus norvegicus) maintained in enclosures of the… Expand
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Highly Cited
2004
Highly Cited
2004
Vitamin K epoxide reductase (VKOR) recycles reduced vitamin K, which is used subsequently as a co-factor in the gamma… Expand
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Highly Cited
2003
Highly Cited
2003
### Mechanism of Action of Coumarin Anticoagulant Drugs Warfarin, a coumarin derivative, produces an anticoagulant effect by… Expand
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Highly Cited
1988
Highly Cited
1988
The mechanism of cephalosporin‐induced hypoprothrombinemia has been investigated in hospitalized patients, with respect to… Expand
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Highly Cited
1988
Highly Cited
1988
Vitamin K 2,3-epoxide reductase activity from liver microsomes requires only a thiol cofactor, particularly dithiothreitol (DTT… Expand
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Highly Cited
1987
Highly Cited
1987
We have evaluated a boy who had excessive bleeding and bruising from birth and showed markedly prolonged prothrombin times… Expand
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Highly Cited
1978