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vitamin D3 25-hydroxylase activity

Known as: cholecalciferol 25-hydroxylase activity 
Catalysis of the reaction: vitamin D3 + NADPH + H+ + O2 = calcidiol + NADP+ + H2O. [ISBN:0471331309, MetaCyc:RXN-9829]
National Institutes of Health

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2 relations

Broader (2)

calcitriol biosynthetic process from calciolvitamin D 25-hydroxylase activity

Papers overview

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2010
2010
[Features of cholecalciferol hydroxylation in the liver of rats in conditions of D-hypervitaminosis and activity of alpha-tocopherol].
It is shown, that hepatocytes contain two (microsomal and mitochondrial) vitamin D3 25-hydroxylase enzymes, which differ as to… 
1991
1991
Characterization of a female-specific hepatic mitochondrial cytochrome P-450 whose steady-state level is modulated by testosterone.
Polyclonal antibody to mitochondrial P-450c27/25 reacted with two proteins of apparent molecular masses of 52 kilodaltons (kDa… 
1984
1984
Inhibition of reconstituted vitamin D3 25-hydroxylase by a protein fraction from rat liver microsomes.
1979
1979
Reconstitution of vitamin D3 25‐hydroxylase activity with a cytochrome P‐450 preparation from rat liver mitochondria
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