vitamin D 25-hydroxylase activity

CONTEXT Inherited forms of vitamin D deficiency are rare causes of rickets and to date have been traced to mutations in three… (More)

The conversion of vitamin D into an active ligand for the vitamin D receptor requires 25-hydroxylation in the liver and 1alpha… (More)

Cimetidine interaction with cytochrome P-450 may reduce binding affinity of some drugs, causing reduced metabolism of substrates… (More)

Bone disease and low serum levels of 25-hydroxyvitamin D are prevalent in cholestatic syndromes such as primary biliary cirrhosis… (More)