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vinyl isoselenocyanate

 
National Institutes of Health

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1 relation

Broader (1)

Organoselenium Compounds

Papers overview

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2020
2020
The PI3K/AKT Pathway Inhibitor ISC-4 Induces Apoptosis and Inhibits Growth of Leukemia in Preclinical Models of Acute Myeloid Leukemia
Acute myeloid leukemia is a heterogeneous disease with a 5-year survival rate of 28.3%, and current treatment options constrained… Expand
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2018
2018
Phenylbutyl isoselenocyanate induces reactive oxygen species to inhibit androgen receptor and to initiate p53‐mediated apoptosis in LNCaP prostate cancer cells
Previous studies have established the in vivo bioavailability and efficacious dosages of phenylbutyl isoselenocyanate (ISC-4), a… Expand
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2012
2012
Phenylalkyl isoselenocyanates vs phenylalkyl isothiocyanates: thiol reactivity and its implications.
Phenylalkyl isoselenocyanate (ISC) compounds were recently designed in our laboratory by incorporating the anticancer element… Expand
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2011
2011
Abstract LB-464: Phenylbutyl isoselenocyanate (ISC-4) and phenylbutyl isothiocyanate (PBITC) inhibit 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induced lung tumorigenesis in A/J mouse
Lung cancer is the leading cause of cancer deaths in both men and women with 90% of cases attributed to tobacco smoking. Evidence… Expand
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