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vinyl isoselenocyanate

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2017
012320072017

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1 relation

Broader (1)

Organoselenium Compounds

Related mentions per year

Related mentions per year

1972-2018
197019801990200020102020
vinyl isoselenocyanate
Organoselenium Compounds

Papers overview

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2018
2018
Phenylbutyl isoselenocyanate induces reactive oxygen species to inhibit androgen receptor and to initiate p53-mediated apoptosis in LNCaP prostate cancer cells.
Previous studies have established the in vivo bioavailability and efficacious dosages of phenylbutyl isoselenocyanate (ISC-4), a… (More)
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2017
2017
Design, synthesis, and identification of a novel napthalamide-isoselenocyanate compound NISC-6 as a dual Topoisomerase-IIα and Akt pathway inhibitor, and evaluation of its anti-melanoma activity.
Synthesis and anti-melanoma activity of novel naphthalimide isoselenocyanate (NISC) and naphthalimide selenourea (NSU) analogs… (More)
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2013
2013
The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer
Phenylbutyl isoselenocyanate (ISC-4) is an Akt inhibitor with demonstrated preclinical efficacy against melanoma and colon cancer… (More)
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2012
2012
Phenylalkyl isoselenocyanates vs phenylalkyl isothiocyanates: thiol reactivity and its implications.
Phenylalkyl isoselenocyanate (ISC) compounds were recently designed in our laboratory by incorporating the anticancer element… (More)
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2012
2012
Synthesis and microwave spectrum of vinyl isoselenocyanate (H2C═CHNCSe), a compound with a quasilinear CNCSe chain.
The first α,β-unsaturated isoselenocyanate, vinyl isoselenocyanate (H(2)C═CHNCSe), has been synthesized, and its microwave… (More)
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2011
2011
The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.
PURPOSE Prostate apoptosis response protein-4 (Par-4) sensitizes cells to chemotherapy; however, Akt1 inactivates Par-4… (More)
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2011
2011
Phenylbutyl isoselenocyanate modulates phase I and II enzymes and inhibits 4-(methylnitrosamino)-1-(3-pyridyl)- 1-butanone-induced DNA adducts in mice.
Lung cancer remains one of the most preventable forms of cancer with about 90% of cases attributed to cigarette smoking. Over the… (More)
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2011
2011
Cancer Therapy: Preclinical The Akt Inhibitor ISC-4 Activates Prostate Apoptosis Response Protein-4 and Reduces Colon Tumor Growth in a Nude Mouse Model
Purpose: Prostate apoptosis response protein-4 (Par-4) sensitizes cells to chemotherapy; however, Akt1 inactivates Par-4… (More)
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2007
2007
The synthesis of 1-thia-6-oxa-6alambda(4)-seleno-3-azapentalene and a 3H-1,2,4-dithiazole.
The reaction of thiocarbamoyl isoselenocyanate with a carbanion gave 1-thia-6-oxa-6alambda(4)-seleno-3-azapentalene, which has a… (More)
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