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vibunazole

Known as: 1-(4-chlorophenoxy)-3,3'-dimethyl-2-(1,2,4-triazol-1-yl)methyl-2-butanol 
National Institutes of Health

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2 relations

Broader (2)

Antifungal AgentsTriazoles

Papers overview

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1994
1994
[Cross-resistance of Candida albicans to several different families of antifungals with ergosterol biosynthesis-inhibiting activity].
Using 9 strains of Candida albicans mutants resistant to either a triazole-antifungal vibunazole, an imidazole-antifungal… 
1988
1988
Vibunazole and Its Enantiomers
Review
1988
Review
1988
Managing fungal and viral infection in the immunocompromised host.
  • U. Jehn
  • Recent results in cancer research. Fortschritte…
  • 1988
  • Corpus ID: 30672035
The increasing number of opportunistic fungal infections in neutropenic cancer patients has become of major concern. Postmortem… 
1987
1987
Action of fluconazole (UK-49,858) in relation to other systemic antifungal azoles.
Viability studies showed that fluconazole (UK-49,858) was strictly fungistatic in its activity against three strains of Candida… 
1986
1986
A diffusion chamber technique for testing of antifungal drugs against Sporothrix schenckii in vivo.
Growth of the yeast form of Sporothrix schenckii (ATCC 14804) was determined in diffusion chambers with 0.45 and 3.0 micron pore… 
1985
1985
New azole compounds: vibunazole (Bay n7133) and Bay L9139, compared with ketoconazole in the therapy of systemic candidosis and in pharmacokinetic studies, in mice.
Ketoconazole, a new imidazole: Bay L9139, and a new triazole: vibunazole (Bay n7133) were compared in therapy of systemic… 
1985
1985
Pharmacokinetics of vibunazole (BAY n 7133) administered orally to healthy subjects.
The role of gastric acidity in the absorption of the new antifungal drug vibunazole was studied in six healthy volunteers… 
Highly Cited
1985
Highly Cited
1985
Penetration of imidazoles and triazoles into cerebrospinal fluid of rabbits.
We studied the penetration of two imidazoles (ketoconazole and vibunazole) and two triazoles (itraconazole and UK-49,858) into… 
Highly Cited
1984
Highly Cited
1984
Antifungal relative inhibition factors: BAY l-9139, bifonazole, butoconazole, isoconazole, itraconazole (R 51211), oxiconazole, Ro 14-4767/002, sulconazole, terconazole and vibunazole (BAY n-7133…
Nine new antifungal agents were tested for their activity in vitro in terms of relative inhibition factors (RIFs) against 26… 
1984
1984
Pharmacokinetics of the oral triazole antimycotic vibunazole in animals.
Methods of assay of the oral triazole antimycotic vibunazole (BAY n 7133) in body fluids by GLC, HPTLC and by a microbiological… 
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